This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-GD2 IgG to TNFα. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the GD2 as well as the biological activity of TNFα. The fusion protein is comprised of an immunoglobulin heavy chain having a specificity for the target cell and a cytokine lymphotoxin, joined via its amino terminal amino acid to the carboxy-terminus of the immunoglobulin. This immunocytokine was designed for treating GD2-positive tumors.
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CAT | Product Name | Application | Type |
---|---|---|---|
NAB-770-sdAb | Recombinant Anti-Human GD2 VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-731 | Anti-GD2 Recombinant Antibody (Dinutuximab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L018R | anti-GD2 immunotoxin 14G2a (IgG)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-304CL | Anti-Human GD2 Recombinant Antibody (hu14.18K322A) | FC, FuncS | Antibody |
PABX-059 | Human Anti-GD2 Recombinant Antibody (PABX-059) | FuncS | IgG1, κ |
PABX-059-F (E) | Human Anti-GD2 Recombinant Antibody; Fab Fragment (PABX-059-F (E)) | FC, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-100 | Mouse Anti-GD2 Recombinant Antibody (clone 14G2a) | ELISA, WB, FuncS | Mouse IgG |
PABL-101 | Mouse Anti-GD2 Recombinant Antibody (clone 3F8) | FC, ELISA, FuncS | Mouse IgG |
FAMAB-0126YC | Mouse Anti-GD2 Recombinant Antibody (clone 7A4) | ELISA | Mouse IgG3, κ |
HPAB-0701-CN | Human Anti-GD2 Recombinant Antibody (clone AB527) | ELISA, FC, IHC, IF | Human IgM |
HPAB-1030WJ | Human Anti-GD2 Recombinant Antibody (HPAB-1030WJ) | ELISA | Chimeric (mouse/human) IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-100 | Mouse Anti-GD2 Recombinant Antibody (clone 14G2a); Fab Fragment | ELISA, WB, FuncS | Mouse Fab |
PFBL-101 | Mouse Anti-GD2 Recombinant Antibody (clone 3F8); Fab Fragment | FC, ELISA, FuncS | Mouse Fab |
PFBZ-049 | Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); Fab Fragment | WB, FuncS | Mouse Fab |
HPAB-0701-CN-F(E) | Human Anti-GD2 Recombinant Antibody (clone AB527); Fab Fragment | ELISA, FC, IHC, IF | Human Fab |
HPAB-0027-WJ-F(E) | Mouse Anti-GD2 Recombinant Antibody; Fab Fragment (HPAB-0027-WJ-F(E)) | ELISA, RIA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-049 | Mouse Anti-GD2 Recombinant Antibody (clone ME36.1); scFv Fragment | WB, FuncS | Mouse scFv |
HPAB-0701-CN-S(P) | Human Anti-GD2 Recombinant Antibody (clone AB527); scFv Fragment | ELISA, FC, IHC, IF | Human scFv |
HPAB-0027-WJ-S(P) | Mouse Anti-GD2 Recombinant Antibody; scFv Fragment (HPAB-0027-WJ-S(P)) | ELISA, RIA | Mouse scFv |
HPAB-1524WJ-S(P) | Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM8138) | ELISA, WB | Human scFv |
HPAB-1525WJ-S(P) | Human Anti-GD2 Recombinant Antibody; scFv Fragment (clone KM1138) | ELISA, WB | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-074CQ | Human Anti-GD2 Recombinant Antibody (TAB-074CQ) | ELISA, FC | Human IgG1, κ |
TAB-075CQ | Human Anti-GD2 Recombinant Antibody (TAB-075CQ) | ELISA, FC | Human IgM, κ |
TAB-076CQ | Human Anti-GD2 Recombinant Antibody (TAB-076CQ) | ELISA, FC | Human IgG1, κ |
TAB-077CQ | Human Anti-GD2 Recombinant Antibody (TAB-077CQ) | ELISA, FC | Human IgG1, κ |
TAB-078CQ | Human Anti-GD2 Recombinant Antibody (TAB-078CQ) | ELISA, FC | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-029CN | Mouse Anti-GD2 Recombinant Antibody (clone 5F11) | WB | Mouse IgG |
NS-030CN | Mouse Anti-GD2 Recombinant Antibody (clone 3G6) | WB | Mouse IgG |
NS-029CN-F(E) | Mouse Anti-GD2 Recombinant Antibody (clone 5F11); Fab Fragment | WB | Mouse Fab |
NS-030CN-F(E) | Mouse Anti-GD2 Recombinant Antibody (clone 3G6); Fab Fragment | WB | Mouse Fab |
NS-029CN-S(P) | Mouse Anti-GD2 Recombinant Antibody (clone 5F11); scFv Fragment | WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-731 | Afuco™ Anti-GD2 ADCC Recombinant Antibody (Dinutuximab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
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