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Anti-GHR Therapeutic Antibody Fab Fragment (GF185) (TAB-262CQ-F(E))

Recombinant monoclonal antibody to GHR. This antibody binds to epitopes that are localized within subdomain 1 of GHR-ECD and is able to neutralize growth hormone (GH) signalling and inhibit GH-induced Ba/F3-GHR proliferation.      

Specifications
Immunogen
GHBP
Host
Mouse
Specificity
Human
Species Reactivity
Human
Clone
GF185
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunoprecipitation; Western Blot
Related Disease
GH-dependent disease
Target
Alternative Names
GHR; growth hormone receptor; GHBP; GH receptor; serum binding protein; somatotropin receptor; growth hormone binding protein
Entrez Gene ID
2690
UniProt ID
P10912

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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