Recombinant monoclonal antibody to GPC3. This product is a mouse monoclonal antibody that can be potentially used in the treatment of hepatocellular carcinoma.
Figure 1 ELISA and flow cytometric analysis of HN3-PE38- and YP7–PE38-binding-affinities for GPC3 protein and G1 cells.
The results are representative of at least three independent experiments.
Gao, W., Tang, Z., Zhang, Y. F., Feng, M., Qian, M., Dimitrov, D. S., & Ho, M. (2015). Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis. Nature communications, 6, 6536.
Figure 2 Inhibition of cell proliferation on different cell lines by HN3-PE38 and YP7-PE38 immunotoxins, determined by a WST-8 assay.
Gao, W., Tang, Z., Zhang, Y. F., Feng, M., Qian, M., Dimitrov, D. S., & Ho, M. (2015). Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis. Nature communications, 6, 6536.
Figure 3 β-Catenin staining and phosphorylated Yap staining on HN3-PE38- and YP7-PE38-treated Hep3B tumours.
Gao, W., Tang, Z., Zhang, Y. F., Feng, M., Qian, M., Dimitrov, D. S., & Ho, M. (2015). Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis. Nature communications, 6, 6536.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NABG-069 | Recombinant Anti-Mouse Gpc3 VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
TAB-416CQ | Anti-Human GPC3 Therapeutic Single Domain Antibody (HN3) | IP, IHC, FuncS, WB, ELISA, Inhib | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H14 | Anti-Human GPC3 Recombinant Antibody (Codrituzumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG1 - kappa |
TAB-160CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-160CT-F(E)) | FC | Humanized Fab |
TAB-161CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-161CT-F(E)) | FC | Humanized Fab |
TAB-162CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-162CT-F(E)) | FC | Humanized Fab |
TAB-163CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-163CT-F(E)) | FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G035E | Anti-Gpc3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0406ZL | Mouse Anti-GPC3 Recombinant Antibody (clone YC080) | WB, IHC, IF, FC | |
MOB-0407ZL | Human Anti-Gpc3 Recombinant Single Domain Antibody (clone YC087) | ELISA, WB, IHC, FuncS | Human VHH |
MOB-140CQ | Mouse Anti-GPC3 Recombinant Antibody (clone YC070) | WB, IHC, IF, FC | Mouse IgG1 |
HPAB-1697LY | Mouse Anti-GPC3 Recombinant Antibody (clone G5S8) | ELISA, IF, Inhib, IHC | Mouse IgG |
HPAB-M0097-YC | Human Anti-GPC3 Recombinant Antibody (clone PA21) | ELISA, WB | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-157CT | Human Anti-GPC3 Recombinant Antibody (TAB-157CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-158CT | Human Anti-GPC3 Recombinant Antibody (TAB-158CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-157CT-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-157CT-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
TAB-158CT-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-158CT-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
TAB-157CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-157CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-167CT | Human Anti-GPC3 Recombinant Antibody (TAB-167CT) | ELISA, FC | Human IgG |
TAB-168CT | Human Anti-GPC3 Recombinant Antibody (TAB-168CT) | ELISA, FC | Human IgG |
TAB-167CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-167CT-S(P)) | ELISA, FC | Human scFv |
TAB-168CT-S(P) | Human Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-168CT-S(P)) | ELISA, FC | Human scFv |
TAB-152CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-152CT-F(E)) | ELISA, FC, IF, WB | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-263CQ-S(P) | Anti-Human GPC3 Recombinant Antibody scFv Fragment (YP7) | ELISA, WB, FC, IHC | |
TAB-263CQ-F(E) | Anti-Human GPC3 Recombinant Antibody Fab Fragment (YP7) | ELISA, WB, FC, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC033 | PE-A*02:01/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-LC034 | APC-A*02:01/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-LC035 | BV421-A*02:01/Human GPC3 (FVGEFFTDV) MHC Tetramer | FCM | |
MHC-LC043 | APC-A*24:02/Human GPC3 (EYILSLEEL) MHC Tetramer | FCM | |
MHC-YF297 | A*02:01/Human GPC3 (FVGEFFTDV) MHC Monomer | MHC Multimer |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1486 | Hi-Affi™ Rabbit Anti-GPC3 Recombinant Antibody (clone DS1486AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0553-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone GES1); Fab Fragment | ELISA, FC, IF, IP | Human Fab |
HPAB-0554-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone huG5S1); Fab Fragment | ELISA, FC, IF, IP | Humanized Fab |
HPAB-0556-CN-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0556-CN-F(E)) | ELISA, WB | Human Fab |
HPAB-0558-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0558-CN-F(E)) | ELISA, WB | Mouse Fab |
HPAB-0560-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0560-CN-F(E)) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1697LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone G5S8); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
HPAB-1698LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES2); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
HPAB-1699LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES6); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
HPAB-1700LY-S(P) | Mouse Anti-GPC3 Recombinant Antibody (clone GES8); scFv Fragment | ELISA, IF, Inhib, IHC | Mouse scFv |
HPAB-0449-FY-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-0449-FY-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H14 | Afuco™ Anti-GPC3 ADCC Recombinant Antibody (Codrituzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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