Products

Anti-GRM2 VHH (DN10) (TAB-0002CL-VHH)

The anti-metabotropic glutamate receptor subtype 2 (mGluR2) conformational single domain antibody target mGluR2 which contribute to the fine-tuning of synaptic efficacy. The llama-derived anti-mGluR2 single domain antibody act as a positive allosteric modulator and are able to stabilized the active state of mGluR2. Therefore, the anti-mGluR2 single domain antibody can be useful in the treatment of schizophrenia, epilepsy, addiction/drug dependence, Parkinson's disease, pain, sleep disorders and Huntington's disease.      

Specifications
Host
Llama
Type
Llama antibody
Specificity
Rat, human
Clone
DN10
Related Disease
Schizophrenia, epilepsy, addiction/drug dependence, Parkinson's disease, pain, sleep disorders, Huntington's disease
Target
Alternative Names
GRM2, GLUR2, GPRC1B, MGLUR2, mGlu2, glutamate metabotropic receptor 2
Entrez Gene ID
2912
UniProt ID
Q14416

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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