This immunotoxin was achieved by conjugating/fusing the Anti-Gpc3 scFv to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating liver cancer.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
NABG-069 | Recombinant Anti-Mouse Gpc3 VHH Single Domain Antibody | WB, ELISA, IHC, FuncS | Llama VHH |
TAB-416CQ | Anti-Human GPC3 Therapeutic Single Domain Antibody (HN3) | IP, IHC, FuncS, WB, ELISA, Inhib | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-152CT | Human Anti-GPC3 Recombinant Antibody (TAB-152CT) | ELISA, FC, IF, WB | Human IgG |
TAB-154CT | Human Anti-GPC3 Recombinant Antibody (TAB-154CT) | ELISA, FC, IF, WB | Human IgG |
TAB-156CT | Human Anti-GPC3 Recombinant Antibody (TAB-156CT) | ELISA, FC, IF, WB | Human IgG |
TAB-152CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-152CT-F(E)) | ELISA, FC, IF, WB | Human Fab |
TAB-265CQ | Anti-Human GPC3 Recombinant Antibody (MDX-1414) | ELISA, WB, FC, IHC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-157CT | Human Anti-GPC3 Recombinant Antibody (TAB-157CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-158CT | Human Anti-GPC3 Recombinant Antibody (TAB-158CT) | ELISA, FC, IHC, WB | Chimeric (mouse/human) IgG1 |
TAB-157CT-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (TAB-157CT-S(P)) | ELISA, FC, IHC, WB | Mouse scFv |
TAB-157CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-157CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
TAB-158CT-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (TAB-158CT-F(E)) | ELISA, FC, IHC, WB | Chimeric (mouse/human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-160CT | Human Anti-GPC3 Recombinant Antibody (TAB-160CT) | FC | Humanized antibody |
TAB-161CT | Human Anti-GPC3 Recombinant Antibody (TAB-161CT) | FC | Humanized antibody |
TAB-162CT | Human Anti-GPC3 Recombinant Antibody (TAB-162CT) | FC | Humanized antibody |
TAB-163CT | Human Anti-GPC3 Recombinant Antibody (TAB-163CT) | FC | Humanized antibody |
TAB-164CT | Human Anti-GPC3 Recombinant Antibody (TAB-164CT) | FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-263CQ | Anti-Human GPC3 Recombinant Antibody (YP7) | ELISA, Inhib, IHC | |
TAB-263CQ-S(P) | Anti-Human GPC3 Recombinant Antibody scFv Fragment (YP7) | ELISA, WB, FC, IHC | |
TAB-263CQ-F(E) | Anti-Human GPC3 Recombinant Antibody Fab Fragment (YP7) | ELISA, WB, FC, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1486 | Hi-Affi™ Rabbit Anti-GPC3 Recombinant Antibody (clone DS1486AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0553-CN-S(P) | Chicken Anti-GPC3 Recombinant Antibody (clone GES1); scFv Fragment | ELISA, FC, IF, IP | Chicken scFv |
HPAB-0554-CN-S(P) | Human Anti-GPC3 Recombinant Antibody (clone huG5S1); scFv Fragment | ELISA, FC, IF, IP | Humanized scFv |
HPAB-0556-CN-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-0556-CN-S(P)) | ELISA, WB | Mouse scFv |
HPAB-0557-CN-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-0557-CN-S(P)) | ELISA, WB | Mouse scFv |
HPAB-0558-CN-S(P) | Mouse Anti-GPC3 Recombinant Antibody; scFv Fragment (HPAB-0558-CN-S(P)) | ELISA, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0553-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone GES1); Fab Fragment | ELISA, FC, IF, IP | Human Fab |
HPAB-0554-CN-F(E) | Human Anti-GPC3 Recombinant Antibody (clone huG5S1); Fab Fragment | ELISA, FC, IF, IP | Humanized Fab |
HPAB-0556-CN-F(E) | Human Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0556-CN-F(E)) | ELISA, WB | Human Fab |
HPAB-0558-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0558-CN-F(E)) | ELISA, WB | Mouse Fab |
HPAB-0560-CN-F(E) | Mouse Anti-GPC3 Recombinant Antibody; Fab Fragment (HPAB-0560-CN-F(E)) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H14 | Afuco™ Anti-GPC3 ADCC Recombinant Antibody (Codrituzumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0689-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0689-WJ) | ELISA, FC, WB | Human IgG |
HPAB-0691-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0691-WJ) | ELISA, FC, WB | Human IgG |
HPAB-0692-WJ | Human Anti-GPC3 Recombinant Antibody (HPAB-0692-WJ) | ELISA, FC, WB | Human IgG |
HPAB-0449-FY | Mouse Anti-GPC3 Recombinant Antibody (HPAB-0449-FY) | ELISA | Mouse IgG2 |
VS3-WK133 | Mouse Anti-GPC3 Recombinant Antibody (clone G3-C2) | WB, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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