Recombinant Human Antibody (UCA) is capable of binding to H1N1 HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-H1N1 HA mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-H1N1 HA proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The UCA antibody binds too weakly for cocrystallization with HA head.
Figure 1 HA binding KD(10⁻⁶ M) and neutralization IC50 (mg/mL)
Raymond, D. D., Stewart, S. M., Lee, J., Ferdman, J., Bajic, G., Do, K. T., ... & Del Giudice, G. (2016). Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. Nature medicine, 22(12), 1465.
Figure 2 Summary of analysis of surface plasmon resonance of Fab binding to immobilized HA (A/Solomon Islands/03/2006) head
Schmidt, A. G., Xu, H., Khan, A. R., O’Donnell, T., Khurana, S., King, L. R., ... & Settembre, E. C. (2013). Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody. Proceedings of the National Academy of Sciences, 110(1), 264-269.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-203 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (3.1) | WB, ELISA, FuncS | Fab |
PFBL-204 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (39.29) | Neut, FuncS | Fab |
PFBL-205 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (1957) | WB, Neut, FuncS | Fab |
PFBL-206 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (1F1) | WB, ELISA, FuncS | Fab |
PFBL-207 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (5J8) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABZ-076 | Recombinant Mouse Anti-IAV HA1 Antibody (26/9) | ELISA | IgG |
PABC-078 | Recombinant Mouse Anti-IAV HA (T131I) Antibody | Neut | IgG |
PABZ-078 | Recombinant Mouse Anti-IAV HA heptapeptide (DVPDYAS) Antibody (17/9) | ELISA | IgG |
PABL-482 | Recombinant Human Anti-H1N1 HA Antibody (CH65) | FuncS, Neut, WB | IgG |
PABL-483 | Recombinant Human Anti-H1N1 HA Antibody (CH67) | IF, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-307CT-S(P) | Anti-IAV HA Recombinant Antibody scFv Fragment (8982) | WB, ELISA | |
MRO-308CT-S(P) | Anti-IAV HA Recombinant Antibody scFv Fragment (8153) | WB, ELISA | |
MRO-309CT-S(P) | Anti-IAV HA Recombinant Antibody scFv Fragment (H36-7) | WB, ELISA | |
MRO-310CT-S(P) | Anti-IAV HA Recombinant Antibody scFv Fragment (H36-5) | WB, ELISA | |
MRO-311CT-S(P) | Anti-IAV HA Recombinant Antibody scFv Fragment (H36-17) | WB, ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-262CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D3-4) | WB, FC, IP | Human antibody |
MRO-263CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-2) | WB, FC, IP | Human antibody |
MRO-264CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-3) | WB, FC, IP | Human antibody |
MRO-265CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-4) | WB, FC, IP | Human antibody |
MRO-266CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-5) | WB, FC, IP | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-070-S (P) | Recombinant Mouse Anti-HA1 Antibody scFv Fragment (Fab17/9) | WB, ELISA, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4209 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI287DS) | ELISA, ICC/IF, IF, FC | IgG |
MOR-4210 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI288DS) | ELISA, ICC/IF, IF, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0765 | PE-DRB1*04:01/Influenza HA (PKYVKQNTLKLAT) MHC Tetramer | FCM, IHC | |
MHC-CN0766 | APC-DRB1*04:01/Influenza HA (PKYVKQNTLKLAT) MHC Tetramer | FCM, IHC | |
MHC-CN0767 | FITC-DRB1*04:01/Influenza HA (PKYVKQNTLKLAT) MHC Tetramer | FCM, IHC | |
MHC-CN0768 | DRB1*04:01/Influenza HA (PKYVKQNTLKLAT) MHC Tetramer | FCM, IHC | |
MHC-YF182 | DRB1*01:01/Influenza HA (PKYVKQNTLKLAT) MHC Monomer | MHC Multimer |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-M0099-YC-S(P) | Recombinant Human Anti-HA Antibody scFv Fragment (Ab 044) | ELISA, FuncS | Human scFv |
HPAB-M0100-YC-S(P) | Recombinant Human Anti-HA Antibody scFv Fragment (FI6) | ELISA, FuncS | Human scFv |
HPAB-M0101-YC-S(P) | Recombinant Human Anti-HA Antibody scFv Fragment (Ab 032) | ELISA, FuncS | Human scFv |
HPAB-0933WJ-S(P) | Recombinant Mouse Anti-HA Antibody scFv Fragment (2F2) | ELISA | Mouse scFv |
HPAB-S0058-YC-S(P) | Mouse Anti-HA Recombinant Antibody (clone HC19); scFv Fragment | Neut | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1169-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1169-FY) | Neut | Llama VHH |
HPAB-1170-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1170-FY) | Neut | Llama VHH |
HPAB-1171-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1171-FY) | Neut | Llama VHH |
HPAB-1172-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1172-FY) | Neut | Llama VHH |
HPAB-1173-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1173-FY) | Neut | Llama VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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