Anti-HCMV Recombinant Antibody (26A1) (CAT#: MRO-1058LC)

This product is a recombinant human anti-Human Cytomegalovirus monoclonal antibody (26A1). 26A1 specifically targets HCMV and can be potentially used in the treatment and diagnosis of human Cytomegalovirus infection.


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Neut

Figure 1 Neutralizing activity of natural (■) and recombinant (○) purified 26A1 IgG.

Figure 1 Neutralizing activity of natural (■) and recombinant (○) purified 26A1 IgG.

The 26A1 mAb was purified from serum-free supernatants by protein A chromatography. The neutralizing activity of HCMV infectivity was then tested either with the laboratory strain AD169 in HELF.

Generation of potent neutralizing human monoclonal antibodies against cytomegalovirus infection from immune B cells

ELISA

Figure 2 gH-specific binding activity of IgG-containing supernatants from subcultures of immortalized human B cells.

Figure 2 gH-specific binding activity of IgG-containing supernatants from subcultures of immortalized human B cells.

The ELISA was performed using the cell culture medium only (medium, negative control), or the supernatant from subcultures 26A1 (described in the patent application EP07110693), 1F7, and two other subcultures known to express hCMV-neutralizing IgG.


Specifications

  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human cytomegalovirus
  • Clone
  • 26A1
  • Applications
  • ELISA, Neut
  • Related Disease
  • Human cytomegalovirus infection

Applications

  • Application Notes
  • The HCMV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Neutralization.

Target

  • Alternative Names
  • Human Cytomegalovirus; HCMV

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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ADCC Enhanced Antibody

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AFC-TAB-894 Afuco™ Anti-HCMV ADCC Recombinant Antibody (Regavirumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

Recombinant Antibody

CAT Product Name Application Type
HPAB-0801-FY Mouse Anti-HCMV Recombinant Antibody (clone 8G8) WB Mouse IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0801-FY-F(E) Mouse Anti-HCMV Recombinant Antibody (clone 8G8); scFv Fragment FC, Neut, ELISA Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0801-FY-S(P) Mouse Anti-HCMV Recombinant Antibody (clone 8G8); Fab Fragment FC, Neut, ELISA Mouse Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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