Anti-HCV E2 Recombinant Antibody (AB68) (CAT#: MRO-1205LC)
This product is a recombinant human anti-Hepatitis C virus monoclonal antibody (AB68). AB68 specifically binds to glycoprotein E2 associated with HCV and can be potentially used in the treatment and diagnosis of Hepatitis C virus infection.
Specific Inquiry
WB
Figure 1. Reactivity of HCV-AB 68 and HCV-AB 65 to E2 constructs by Western blot analysis.
Samples prepared at 37°C. Lanes: 1, His-EK-E2; 2, His-EK-E2-without HVR1; 3, E2 MCS; 4, E2 MCS without HVR1; 5, E2-CHO.
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
IHC
Figure 2. HCV-AB 68 with HCV-infected liver (magnification, ×40).
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
IP
Figure 3. Immunoprecipitation by HCV-AB 68 (in quadruplicates) and HBV-AB 17 as an isotype control (in duplicates).
Immunoprecipitation of virus particles from HCV-infected sera from different genotypes by HCV-AB 68 and HCV-AB 65.
Eren, R., Landstein, D., Terkieltaub, D., Nussbaum, O., Zauberman, A., Ben-Porath, J., ... & Aviel, S. (2006). Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients. Journal of virology, 80(6), 2654-2664.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Hepatitis C virus
- Clone
- AB68
- Applications
- WB, IP, IHC
- Related Disease
- Hepatitis C virus infection
Applications
- Application Notes
- The AB68 antibody has been reported in applications of WB, IHC, IP.
It's recommended that the optimal antibody concentration, dilution, incubation time etc. are best to be carefully titrated in specific assays. For details, refer to Published Data.
Target
- Alternative Names
- Hepatitis C virus; HCV; HCV E2; Hepatitis C virus E2
- Gene ID
- 951475
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone AB68"
See other products for "HCV E2 protein"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-492 | Mouse Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (PFBL-492) | ELISA, Neut | Mouse Fab |
| PFBL-493 | Recombinant Mouse Anti-HCV E2 Antibody Fab Fragment (AP33) | ELISA | Fab |
| PFBL-494 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (AR3C) | Neut | Fab |
| PFBL-495 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (C2) | Neut | Fab |
| PFBL-496 | Recombinant Human Anti-HCV E2 Antibody Fab Fragment (HC33.8) | Neut | Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-476LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-476LC) | ELISA, Inhib | Chimeric (mouse/human) IgG |
| MRO-476LC-S(P) | Mouse Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-476LC-S(P)) | ELISA | Mouse scFv |
| MRO-476LC-F(E) | Human Anti-HCV E2 Protein Recombinant Antibody; Fab Fragment (MRO-476LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-477LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-477LC) | ELISA | Humanized IgG1, κ |
| MRO-478LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-478LC) | ELISA | Humanized IgG1, κ |
| MRO-479LC | Human Anti-HCV E2 Protein Recombinant Antibody (MRO-479LC) | ELISA | Humanized IgG1, κ |
| MRO-477LC-S(P) | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-477LC-S(P)) | ELISA | Humanized scFv |
| MRO-478LC-S(P) | Human Anti-HCV E2 Protein Recombinant Antibody; scFv Fragment (MRO-478LC-S(P)) | ELISA | Humanized scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-529LC | Anti-HCV E2 Recombinant Antibody (7) | ELISA | Human antibody |
| MRO-485LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (AB 68) | ELISA | Human antibody |
| MRO-488LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (CBH-4D) | ELISA, WB | Human antibody |
| MRO-489LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (CBH-4B) | ELISA, WB | Human antibody |
| MRO-490LC-F(E) | Anti-HCV E2 Recombinant Antibody Fab Fragment (CBH-4G) | ELISA, WB | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1191LC | Anti-HCV E2 Recombinant Antibody (A10F2) | ELISA, Inhib | Mouse Antibody |
| MRO-1192LC | Anti-HCV E2 Recombinant Antibody (H6D3) | ELISA, Inhib, WB | Mouse Antibody |
| MRO-1193LC | Anti-HCV E2 Recombinant Antibody (E3D8) | ELISA, Inhib, WB | Mouse Antibody |
| MRO-1194LC | Anti-HCV E2 Recombinant Antibody (A7A6H9) | ELISA, Inhib | Mouse Antibody |
| MRO-1195LC | Anti-HCV E2 Recombinant Antibody (G9E1) | ELISA, Inhib | Mouse Antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC428 | PE-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM | |
| MHC-LC429 | APC-A*24:02/HCV E2 (EYVLLLFLL) MHC Tetramer | FCM |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0065LC | Recombinant Mouse Anti-HCV E2 protein Antibody (JS-81) | ELISA | IgG1 |
| EPAF-1294LC | Recombinant Human Anti-HCV E2 protein Antibody (4c2) | ELISA |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-415 | Human Anti-HCV E2 Protein Recombinant Antibody (PABC-415) | ELISA, IP, Neut, Inhib, FC | Human IgG1 |
| FAMAB-0174WJ | Human Anti-HCV E2 Recombinant Antibody (clone 212.1.1) | ELISA, WB, Neut | Human IgG1 |
| HPAB-1522WJ | Human Anti-HCV E2 protein Recombinant Antibody (clone A8) | ELISA, WB | Human IgG |
| HPAB-1523WJ | Human Anti-HCV E2 protein Recombinant Antibody (clone A12) | ELISA, WB | Human IgG |
| VS-0723-XY14 | Recombinant Human Anti-HCV E1E2 Antibody (clone HC1AM) | ELISA, Neut | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-282 | Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HC26AM) | ELISA, Neut | Human scFv |
| PSBC-474 | Recombinant Human Anti-HCV E2 Antibody scFv Fragment (HCV1-C1) | ELISA, Neut | Human scFv |
| FAMAB-0198JF-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone L1); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| FAMAB-0358JF-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone 9e1); scFv Fragment | ELISA, FuncS | Human scFv |
| FAMAB-0174WJ-S(P) | Human Anti-HCV E2 Recombinant Antibody (clone 212.1.1); scFv Fragment | ELISA, WB, Neut | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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