Anti-Human HIF-1alpha Recombinant Antibody (6H4) (CAT#: TAB-082CT)

Recombinant monoclonal antibody (6H4) to HIF-1alpha. The isotype is mouse IgG1. The antibody has been tested in western blot (1/100) with cell Lysates and Immunofluorescence (1/100) assays. This antibody intended for the prophylaxis and treatment studies of Pancreatic cancer, Colorectal cancer.


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  • Published Data
  • Gene Expression
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  • MSDS
  • COA
WB

Figure 1 Validation of monoclonal antibodies against hydroxylated proline 402 or 564 containing peptides of the HIF-1α ODD region.

Figure 1 Validation of monoclonal antibodies against hydroxylated proline 402 or 564 containing peptides of the HIF-1α ODD region.

Clones 6H4 recognized specifically HIF-1α hydroxylated at proline 402 as demonstrated by Western blotting of lysates of JEG-3 cells transfected with a HIF-1α single or double mutated construct at P402 and/or P564.

Rolfo, A., Many, A., Racano, A., Tal, R., Tagliaferro, A., Ietta, F., ... & Caniggia, I. (2010). Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies. PloS one, 5(10), e13288.


Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • 6H4
  • Applications
  • WB
  • Related Disease
  • Pancreatic cancer, Colorectal cancer

Applications

  • Application Notes
  • This antibody has been reported for use in Western Blot.

Target

  • Alternative Names
  • HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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