Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (A10F9) (CAT#: PABX-089-S (P))

Anti-HIV-1 antibody is a Mouse of scFv class that binds to an HIV-1.


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Figure 1 SDS-PAGE and western blotting of the assembled CA N21C/A22C-V5.

Figure 1 SDS-PAGE and western blotting of the assembled CA N21C/A22C-V5.

Lane M, molecular weight marker; lane 1, protein before assembly; lane 2-5, protein after assembly. The primary antibody is a CA specific mAb A10F11.

Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.

Figure 2 Antigenicity of CA N21C/A22C-V3 was determined with the A10F11 mAb using indirect ELISA.

Figure 2 Antigenicity of CA N21C/A22C-V3 was determined with the A10F11 mAb using indirect ELISA.

Data were analyzed by GraphPad Prism software. The 50% maximal effective concentration (EC52) was calculated by a four-parameter logistic fit, and is indicated in the square brackets.

Zhang, Z., He, M., Bai, S., Zhang, F., Jiang, J., Zheng, Q., ... & Xia, N. (2018). T= 4 Icosahedral HIV-1 Capsid As an Immunogenic Vector for HIV-1 V3 Loop Epitope Display. Viruses, 10(12), 667.

Figure 3 Ribbon representation of a detailed view of p24 CTD recognition by the A10F11 Fab fragment.

Figure 3 Ribbon representation of a detailed view of p24 CTD recognition by the A10F11 Fab fragment.

The residues involved in protein-protein interactions are indicated and shown in stick mode.

Gu, Y., Cao, F., Wang, L., Hou, W., Zhang, J., Hew, C. L., ... & Xia, N. (2013). Structure of a novel shoulder-to-shoulder p24 dimer in complex with the broad-spectrum antibody A10F9 and its implication in capsid assembly. PloS one, 8(4), e61316.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • scFv
  • Specificity
  • Tested positive against native D. pteronyssinus Derp1
  • Species Reactivity
  • Human immunodeficiency virus 1
  • Clone
  • A10F9
  • Applications
  • Neut (assay-depended)
    FuncS (assay-depended)

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Applications

  • Application Notes
  • Assay-depended

Target

  • Alternative Names
  • HIV-1; human immunodeficiency virus

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Single-domain Antibody

CAT Product Name Application Type
NAB-1889-sdAb Recombinant Anti-HIV-1 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH
PNBL-038 Recombinant Anti-HIV-1 C186 gp120 VHH Single Domain Antibody (A12) WB, FuncS Llama VHH

Humanized Antibody

Immunotoxin

CAT Product Name Application Type
AGTO-G037E Anti-HIV-1 immunotoxin 3B3 (scFv)-PE Cytotoxicity assay, Function study
AGTO-G037D Anti-HIV-1 immunotoxin 3B3 (scFv)-DT Cytotoxicity assay, Function study

Chimeric Antibody

CAT Product Name Application Type
PABX-093-S (P) Recombinant Mouse Anti-HIV-1 Antibody scFv Fragment (Fab28) WB, ELISA, FuncS scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4221 Rabbit Anti-HIV-1 Recombinant Antibody (clone SI300DS) ELISA, ICC, IF, FC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-068 Afuco™ Anti-HIV-1 ADCC Recombinant Antibody (Suvizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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