Recombinant Human Antibody (C1-28) is capable of binding to HIV-1 Nef134-10(2F), expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 Nef134-10(2F) mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-HIV-1 Nef134-10(2F) proteins mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 Cytolytic activities of HLA-A24-restricted Nef134-10-specific CTL clones derived from HLA-A24-positive HIV-1-infected patients.
Clones C1-28 killed HLA-A24-positive target cells pulsed with log-fold dilutions of Nef134-10 peptides, Nef134-10(wt); blue, Nef134-10(2F); red. The effector-versus-target ratio was 5:1.
Shimizu, A., Kawana-Tachikawa, A., Yamagata, A., Han, C., Zhu, D., Sato, Y., ... & Brumme, C. J. (2013). Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection. Scientific reports, 3(1), 1-9.
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• Confirmed specificity
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• Excellent batch-to-batch consistency
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-013 | Recombinant Anti-HIV nef VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-562 | Human Anti-HIV-1 Nef Recombinant Antibody (clone C1-28); scFv Fragment | FC | Human scFv |
PSBL-563 | Human Anti-HIV-1 Nef Recombinant Antibody (clone H27-14); scFv Fragment | FC | Human scFv |
MRO-4205CQ-S(P) | Human Anti-HIV-1 Nef Recombinant Antibody (clone 3B4B); scFv Fragment | ELISA | Human scFv |
MRO-4233CQ-S(P) | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 6.1); scFv Fragment | IHC | Mouse scFv |
MRO-4234CQ-S(P) | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 13/042); scFv Fragment | ELISA, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-887CQ | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 01-004) | WB, IHC-P, IF | Mouse IgG1 |
MRO-888CQ | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 01-009) | WB, IHC-P, IF | Mouse IgG1 |
MRO-889CQ | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 01-011) | WB | Mouse IgG1 |
MRO-890CQ | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 2F2) | ELISA, WB, IHC | Mouse IgG |
MRO-891CQ | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 2H12) | ELISA, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-4205CQ-F(E) | Human Anti-HIV-1 Nef Recombinant Antibody (clone 3B4B); Fab Fragment | ELISA | Human Fab |
MRO-4206CQ-F(E) | Human Anti-HIV-1 Nef Recombinant Antibody (clone 4H4); Fab Fragment | ELISA, IF, FC | Human Fab |
MRO-4207CQ-F(E) | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 2A3); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
MRO-4208CQ-F(E) | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 2EA); Fab Fragment | ELISA, WB, IHC | Mouse Fab |
MRO-4209CQ-F(E) | Mouse Anti-HIV-1 Nef Recombinant Antibody (clone 2F2); Fab Fragment | ELISA, WB | Mouse Fab |
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