Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) (CAT#: MRO-135LC)
This product is a recombinant chimeric (mouse/human) anti-HIV-1 monoclonal antibody. CAG1-51-4 specifically binds to CD4 binding site of gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.
Specific Inquiry
Neut
Figure 1 shows the neutralizing activities of chimeric antibody on the infection of H9 cells by HIV-1.
Cell-free culture supernatants were col¬ lected at day 14 for HIV-1 specific antigen capture assays after the H9 cells were challenged with HIV-1 in the absence and in the presence of antibody tested. Each concentration of the antibodies was tested in triplicate. The inhibition of HIV-1 infection was calculated by comparing the optical densities obtained in the antigen capture assays of cultures infected with the virus in the presence of antibody to the negative control without added antibody. The antibodies tested were BAT123 (O), Chimeric antibody cAGl-51-4 (•), and a non-reactive murine anti-hcG antibody (Δ). Deta iled Des cription of the Invention.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric antibody (mouse/human)
- Specificity
- HIV-1
- Clone
- CAG1-51-4
- Applications
- ELISA, WB, Neut
- Related Disease
- AIDS
Applications
- Application Notes
- The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Neutralization.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- Gene ID
- 155971
- UniProt ID
- P04578
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone CAG1-51-4"
See other products for "HIV-1 gp120"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-380 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC06) | FC, Neut, FuncS | Human IgG |
| PABZ-060 | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone 50.1) | Neut | Mouse IgG2a, κ |
| PABL-520 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 44-VRC13.01) | Neut | Human IgG |
| PABL-521 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-46M2) | ELISA, Neut | Human IgG |
| PABL-522 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 45-VRC01.H5.F-185917) | WB, FuncS | Human IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
| MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91H9) | ELISA | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
| MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
| MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
| MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
| MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-041LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (D59/A2) | ELISA | Mouse antibody |
| MRO-042LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (F58/H3) | ELISA | Mouse antibody |
| MRO-043LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P1/D12) | ELISA | Mouse antibody |
| MRO-044LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P4/D10) | ELISA | Mouse antibody |
| MRO-045LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (A47/B1) | ELISA | Mouse antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0177CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone BAT123); Fab Fragment | Neut | Chimeric (mouse/human) Fab |
| FAMAB-0178CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone C beta 1); Fab Fragment | WB, Neut | Chimeric (mouse/human) Fab |
| MRO-2927CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1-74); Fab Fragment | Neut | Human Fab |
| MRO-2928CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 2-1261); Fab Fragment | Neut | Human Fab |
| MRO-2929CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 9-201); Fab Fragment | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3527CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1108); scFv Fragment | Neut | Human scFv |
| MRO-3528CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT133); scFv Fragment | ELISA, FC | Human scFv |
| MRO-3529CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT134); scFv Fragment | ELISA, FC | Human scFv |
| MRO-3530CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 13A2); scFv Fragment | ELISA | Humanized scFv |
| MRO-3531CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 13C); scFv Fragment | ELISA | Humanized scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MRO-135LC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.