Human Anti-HIV-1 gp120 Recombinant Antibody (clone 2909) (CAT#: PABL-531)

Recombinant Human Antibody (mAb2909) is capable of binding to HIV-1 gp120, expressed in HEK 293 cells.


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Figure 1 Immunoprecipitation of binding of human mAb 2909 to virions and transfected cells.

Figure 1 Immunoprecipitation of binding of human mAb 2909 to virions and transfected cells.

Monoclonal Ab 2909 immunoprecipitated SF162 WT pseudoviruses but not those expressing SF162 mut or mock virus which does not express Env proteins. Monoclonal Ab 447 (anti-V3) precipitated both viruses and the control anti-parvovirus mAb 1418 did not precipitate any of the pseudoviruses.

Kimura, T., Wang, X. H., Williams, C., Zolla-Pazner, S., & Gorny, M. K. (2009). Human monoclonal antibody 2909 binds to pseudovirions expressing trimers but not monomeric HIV-1 envelope proteins. Human antibodies, 18(1, 2), 35-40.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1,λ
  • Specificity
  • Tested positive against HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • 2909
  • Applications
  • IP Assay-dependent
    Neut Assay-dependent

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Assay-dependent

Target

  • Alternative Names
  • ENV; gp160; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 2909"

See other products for "HIV-1 gp120"

Single-domain Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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