Recombinant Human Anti-HLA-A Antibody (T1) (CAT#: PABX-105)

Anti-HLA-A antibody is a Human antibody of IgG class that binds to an HLA-A. This antibody achieved 2-to 4-nM affinities to HIV-2.


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FC

Figure 1 Crystal structure of T1 Fab binding HLA-A2/NYESO1, with highlighting of targeted amino acids.

Figure 1 Crystal structure of T1 Fab binding HLA-A2/NYESO1, with highlighting of targeted amino acids.

Maus, M. V., Plotkin, J., Jakka, G., Stewart-Jones, G., Rivière, I., Merghoub, T., ... & Sadelain, M. (2016). An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity. Molecular Therapy-Oncolytics, 3, 16023.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG
  • Specificity
  • Tested positive against native Human HLA-A
  • Species Reactivity
  • Human
  • Clone
  • T1
  • Applications
  • Can be useful in applications such as: Western blot; Enzyme-linked Immunosorbent Assay; Functional Study

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • HLA-A; major histocompatibility complex, class I, A; HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Immunotoxin

CAT Product Name Application Type
AGTO-L022F anti-HLA-A immunotoxin Fib75 (IgG)-α-sar Cytotoxicity assay, Functional assay

Human Antibody

CAT Product Name Application Type
PABX-105-S (P) Recombinant Human Anti-HLA-A Antibody scFv Fragment (T1) WB, ELISA, FuncS scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1617 Rabbit Anti-HLA-A Recombinant Antibody (clone DS1617AB) FC, ICC, IF, IHC-Fr, IHC-P, IP, WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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