Anti-Human HLA-DR Recombinant Antibody ( L243) (CAT#: TAB-094CT)

Provided is a recombinant monoclonal antibody L243 to HLA-DR. The antibody was generated from a hybridoma cell line.


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FC

Figure 1 Anti-HLA-DR antibody L243 induces apoptosis and G2 arrest in NF1-/- SCs.

Figure 1 Anti-HLA-DR antibody L243 induces apoptosis and G2 arrest in NF1-/- SCs.

Induction of apoptosis was evaluated by flow cytometry determination of terminal transferase dUTP nick-end labeling (TUNEL) staining (2.5 hours).

Reuss, D. E., Mucha, J., Holtkamp, N., Müller, U., Berlien, H. P., Mautner, V. F., ... & Von Deimling, A. (2013). Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells. The Journal of investigative dermatology, 133(5), 1372.

Inhib

Figure 2 Anti-HLA-DR antibody L243 induces apoptosis and G2 arrest in NF1-/- SCs.

Figure 2 Anti-HLA-DR antibody L243 induces apoptosis and G2 arrest in NF1-/- SCs.

Cell growth of NF1-/- SCs (ID34) upon incubation with L234 or IgG within 24 hours.

Reuss, D. E., Mucha, J., Holtkamp, N., Müller, U., Berlien, H. P., Mautner, V. F., ... & Von Deimling, A. (2013). Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells. The Journal of investigative dermatology, 133(5), 1372.


Specifications

  • Host Species
  • Mouse
  • Derivation
  • Hybridoma cell line
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • L243
  • Applications
  • FC, Inhib

Applications

  • Application Notes
  • This antibody has been reported for use in Flow Cytometry and Inhibition.

Target

  • Alternative Names
  • HLA-DR; Human Leukocyte Antigen-DR; L243

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Humanized Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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