Recombinant Anti-HPV16 E7 Intrabody [(D-Arg)9] (CAT#: IAB-B047(A))

Recombinant anti-HPV16 E7 intrabody linked to (D-Arg)9 works within cells and specifically reacts with HPV16 E7, expressed in 293T cells. The intrabody is specific for the E7 oncoprotein of HPV16 and is able to inhibit cell proliferation.


Specific Inquiry
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  • Datasheet
  • MSDS
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Specifications

  • Immunogen
  • Human papillomavirus16 transforming protein
  • Host Species
  • mouse
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • HPV16
  • Applications
  • Products can be used for: Immunocytochemistry; Neutralization; Functional studies

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

Target

  • Alternative Names
  • E7; transforming protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HPV16 E7"

Intrabody

CAT Product Name Application Type
IAB-B047(G) Recombinant Anti-HPV16 E7 Intrabody [+36 GFP] ELISA, WB, ICC, FuncS scFv-(+36GFP)
IAB-B047(T) Recombinant Anti-HPV16 E7 Intrabody [Tat] IF, FC, WB, FuncS scFv-Tat

Mouse Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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