Recombinant Anti-human HTT Intrabody [+36 GFP] (CAT#: IAB-B023(G))

Recombinant anti-HTT intrabody in fusion with +36GFP works within cells to bind htt and prevent aggregation, show promise as immunotherapeutics for HD, expressed in 293T cells. The anti-huntingtin intrabody can degrade mutant huntingtin proteins by directing them to the proteasome, while also increasing the negative charge.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue

Specifications

  • Immunogen
  • human Huntingtin
  • Host Species
  • human
  • Type
  • scFv-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • human
  • Applications
  • Can be useful in applications such as: Immunofluorescence; Flow Cytometry; Western blot; Functional studies

Product Property

  • Purity
  • >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
  • Storage
  • ≤6 months at 4°C; ≥6 months at -20°C.

Target

  • Alternative Names
  • HTT; huntingtin; HD; IT15; huntington disease protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HTT"

Single-domain Antibody

CAT Product Name Application Type
NAB-1905-VHH Recombinant Anti-human HTT VHH Single Domain Antibody IHC, ICC, FC, FA, FUNC Llama VHH
PABJ-0201 Human Anti-HTT Recombinant Antibody (clone 3LRH) ELISA, FuncS Human VL

Intrabody

CAT Product Name Application Type
IAB-B023(A) Recombinant Anti-human HTT Intrabody [(D-Arg)9] ELISA, WB, ICC, FuncS scFv-(D-Arg)9
IAB-B023(T) Recombinant Anti-human HTT Intrabody [Tat] WB, CO-IP, FuncS scFv-Tat

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1714 Rabbit Anti-HTT Recombinant Antibody (clone DS1714AB) WB, IHC-P, ICC Rabbit IgG
MOR-0066-FY Rabbit Anti-HTT Recombinant Antibody (clone AFY0037) FC, ICC, IHC, WB Rabbit IgG

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for IAB-B023(G). Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare