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Taplitumomab paptox (TAB-174)

Recombinant monoclonal antibody to CD19. Taplitumomab paptox is a mouse monoclonal antibody designed for the treatment of cancer The antibody itself, taplitumomab, is linked to the protein PAP, an antiviral from Phytolacca americana, a species of pokeweed. This is reflected by the 'paptox' in the drug's name.      

Specifications
Immunogen
Mouse CD19-expressing K562 human erythroleukemia cells
Host
Mouse
Derivation
Mouse
Type
IgG1 - kappa
Specificity
Tested positive against native human antigen.
Species Reactivity
Human
Applications
Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
CAS NO.
235428-87-2
Generic Name
Taplitumomab paptox
Related Disease
Cancers
Target
Alternative Names
Taplitumomab paptox; 235428-87-2; B43; CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19
Entrez Gene ID
930
UniProt ID
P15391

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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