Products

Tositumomab (TAB-017)

Recombinant monoclonal antibody to Human CD20. Tositumomab is a drug for the treatment of follicular lymphoma. It is an IgG2a anti-CD20 monoclonal antibody derived from immortalized mouse cells. Tositumomab is applied in a sequential infusion followed by iodine (131I) tositumomab, which is the same antibody covalently bound to the radionuclide iodine-131 (131I). 131I emits both beta and gamma radiation and decays with a half-life of 8 days.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG2a - lambda
Specificity
Tested positive against native human antigen
Species Reactivity
Human
Applications
Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, ICC and most other immunological methods.
Trade name
bexxar
CAS NO.
192391-48-3
Generic Name
Tositumomab
ATC Code
V10XA53
DrugBank
DB00081
UNII
0343IGH41U
ChEMBL
CHEMBL1201604
M.W.
143,859.7 g/mol
Related Disease
Non-Hodgkin's lymphoma (NHL) (follicular, CD20 positive, following chemotherapy relapse)
Target
Alternative Names
Tositumomab; bexxar; 192391-48-3; DB00081 MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1
Entrez Gene ID
931
UniProt ID
P11836

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved