Humanized Anti-CD22 Recombinant Antibody (clone Inotuzumab) (CAT#: TAB-198)

This product is a humanized (from mouse) IgG4, κ antibody that can recognize human CD22.


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ELISA

Figure 1 Anti-CD22 Antibody (TAB-198) in ELISA

Figure 1 Anti-CD22 Antibody (TAB-198) in ELISA

ELISA analysis of TAB-198 was performed by coating with CD22 Protein, Human, Recombinant (His Tag).
The secondary antibody: HRP-Anti-Human IgG (H+L)

WB

Figure 2 Anti-CD22 Antibody (TAB-198) in WB

Figure 2 Anti-CD22 Antibody (TAB-198) in WB

Western blot analysis of TAB-198 was performed with CD22 Protein, Human, Recombinant (His Tag).
TAB-198 incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.6μg)

DB

Figure 3 Anti-CD22 Antibody (TAB-198) in DB

Figure 3 Anti-CD22 Antibody (TAB-198) in DB

Dot blot analysis of TAB-198 was performed with CD22 Protein, Human, Recombinant (His Tag).
TAB-198 incubation concentration: 2ng/μL.
NC: Negative control PC: Positive control

FC

Figure 4 Anti-CD22 Antibody (TAB-198) in Flow Cytometry

Figure 4 Anti-CD22 Antibody (TAB-198) in Flow Cytometry

Flow cytometry analysis of Daudi cells with anti-CD22 antibody (Cat#TAB-198, Blue line) or isotype control antibody (Yellow line). A Goat Anti-human IgG (FITC) was used as the secondary antibody.


Specifications

  • Immunogen
  • Human tonsil lymphocytes
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • Humanized (from mouse) IgG4, κ
  • Specificity
  • Human CD22
  • Species Reactivity
  • Human
  • Clone
  • Inotuzumab
  • Applications
  • ELISA, FC, IP, FuncS, IF, Neut, ICC

Product Property

  • Purification
  • Protein A/G Purified
  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunoprecipitation, Functional Assay, Immunofluorescence, Neutralization, Immunocytochemistry.

Target

  • Alternative Names
  • SIGLEC2; SIGLEC-2; B-cell receptor CD22; B-lymphocyte cell adhesion molecule; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; sialic acid-binding Ig-like lectin 2

Related Resources

  • Biosimilar Overview
Please refer to Inotuzumab Ozogamicin Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Inotuzumab Ozogamicin.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Inotuzumab"

See other products for "CD22"

Immunotoxin

CAT Product Name Application Type
AGTO-L048E anti-CD22 immunotoxin RFB4 (scFv)-PE Cytotoxicity assay, Functional assay
AGTO-L048D anti-CD22 immunotoxin RFB4 (scFv)-DT Cytotoxicity assay, Functional assay
AGTO-L048G anti-CD22 immunotoxin RFB4 (scFv)-Gel Cytotoxicity assay, Functional assay
AGTO-L048R anti-CD22 immunotoxin RFB4 (scFv)-RTA Cytotoxicity assay, Functional assay
AGTO-L048S anti-CD22 immunotoxin RFB4 (scFv)-Sap Cytotoxicity assay, Functional assay

Fab Glycosylation

CAT Product Name Application Type
Gly-001LC Recombinant Anti-Human CD22 Antibody (Fab glycosylation) ELISA, FC Mouse antibody

Fc Glycosylation

CAT Product Name Application Type
Gly-111LC Recombinant Anti-Human CD22 Antibody (Fc glycosylation) ELISA Chimeric antibody (mouse/human)

Blocking Antibody

CAT Product Name Application Type
NEUT-315CQ Rat Anti-CD22 Recombinant Antibody (clone 2D6) Block Rat IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0545 Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) IP, WB Rabbit IgG

Recombinant Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-176 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Epratuzumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-198 Afuco™ Anti-CD22 ADCC Recombinant Antibody (Inotuzumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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