Anti-Human CD23 Recombinant Antibody (Gomiliximab) (CAT#: TAB-231)

Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.


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WB

Figure 1 Anti-Human CD23 Recombinant Antibody (Gomiliximab) (TAB-231) in WB

Figure 1 Anti-Human CD23 Recombinant Antibody (Gomiliximab) (TAB-231) in WB

Western blot analysis of TAB-231 was performed with Recombinant Human CD23 Protein onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-231 and HRP Anti-Human IgG as a secondary antibody. Chemiluminescent detection was performed.

ELISA

Figure 2 Anti-Human CD23 Recombinant Antibody (Gomiliximab) (TAB-231) in ELISA

Figure 2 Anti-Human CD23 Recombinant Antibody (Gomiliximab) (TAB-231) in ELISA

ELISA analysis of TAB-231 was performed by coating with Recombinant Human CD23 Protein. Then blocked with BSA, and incubated with Anti-Human CD23 Antibody (TAB-231). The HRP-conjugated anti-human IgG as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • primate
  • Derivation
  • Chimeric (primate/human)
  • Type
  • IgG1 - kappa
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in WB, Neut, ELISA, IF, IP, FuncS, FC and most other immunological methods.
  • CAS
  • 357613-86-6
  • Generic Name
  • Gomiliximab
  • UNII
  • 8Z13S29R5A

Product Property

  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • Gomiliximab;357613-86-6;FCER2;Fc fragment of IgE, low affinity II, receptor for (CD23);CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2;low affinity immunoglobulin epsilon Fc receptor;CD23;CLEC4J;BLAST-2;CD23 antigen;fc-epsilon-RII;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Gomiliximab"

Afuco™ Anti-FCER2 ADCC Recombinant Antibody (Gomiliximab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.

See other products for "FCER2"

Fc Glycosylation

CAT Product Name Application Type
Gly-157LC Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) ELISA Chimeric antibody (primate/human)

Low- or Non-fucosylated Oligosaccharide

CAT Product Name Application Type
Gly-157LC-1 Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) ELISA Chimeric antibody (primate/human)

Neutralizing Antibody

CAT Product Name Application Type
NEUT-786CQ Mouse Anti-FCER2 Recombinant Antibody (clone CBL016) Neut, FC, WB Mouse IgG2
NEUT-788CQ Mouse Anti-FCER2 Recombinant Antibody (clone MM0164-2C23) WB, Neut, FC Mouse IgG1

Blocking Antibody

CAT Product Name Application Type
NEUT-787CQ Mouse Anti-FCER2 Recombinant Antibody (clone TU1) FC, IHC-Fr, ICC, WB, Block Mouse IgG3, κ
NEUT-789CQ Mouse Anti-FCER2 Recombinant Antibody (clone CBL329) ELISA, WB, Block, CyTOF®, FC Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1268 Hi-Affi™ Rabbit Anti-FCER2 Recombinant Antibody (clone DS1268AB) IHC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-231 Afuco™ Anti-FCER2 ADCC Recombinant Antibody (Gomiliximab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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