Anti-Human EGFL7 Recombinant Antibody (Parsatuzumab) (CAT#: TAB-902)
Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
Specific Inquiry
Inhib
Figure 1 EGFL7 in LSCs.
Anti-EGFL7 (Parsatuzumab) antibody or IgGl control (vs Unstim)
Inhib
Figure 2 Parsatuzumab decreases blast growth and activation of NOTCH downstream signaling.
CFUs on primary AML blasts treated with anti- EGFL7 vs. IGgl controls.
Block
Figure 3 Blocking EGFL7 increases the NOTCH downstream target, HEY1, in human AML patient blasts.
Primary blasts from AML patients were cultured in SFEM medium with 10% FBS in the absence or presence of 100 μg/ml of IgG or anti- human EGFL7 antibody for 2 and 10 h.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Block
- CAS
- 1312797-14-0
- Generic Name
- Parsatuzumab
- MW
- 147.8 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Human EGFL7 antibody has been reported in applications of Blocking.
Block: 100 μg/ml.
Target
- Alternative Names
- Parsatuzumab;1312797-14-0;RG7414;MEGF0444A;EGFL7;EGF-like-domain, multiple 7;epidermal growth factor-like protein 7;ZNEU1;EGF-like protein 7;NOTCH4-like protein;vascular endothelial statin;multiple EGF-like domains protein 7;multiple epidermal growth fact
- Gene ID
- 51162
- UniProt ID
- Q9UHF1
Related Resources
Please refer to Parsatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Parsatuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Parsatuzumab"
Afuco™ Anti-EGFL7 ADCC Recombinant Antibody (Parsatuzumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human EGFL7. Parsatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator and binds to EGFL7.
See other products for "EGFL7"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-834-VHH | Recombinant Anti-Human EGFL7 VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2365MZ | Recombinant Mouse Anti-Human EGFL7 Antibody | WB | Mouse antibody |
| HPAB-0002-DJB | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9) | ELISA, WB | Mouse IgG2b |
| HPAB-0003-DJB | Mouse Anti-EGFL7 Recombinant Antibody (HPAB-0003-DJB) | ELISA, WB | Mouse IgG2b |
| HPAB-0951WJ | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1) | ELISA | Mouse IgG |
| HPAB-0952WJ | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17) | ELISA | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0002-DJB-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9); scFv Fragment | ELISA, WB | Mouse scFv |
| HPAB-0951WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0952WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0953WJ-S(P) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v22); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0002-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 10G9); Fab Fragment | ELISA, WB | Mouse Fab |
| HPAB-0003-DJB-F(E) | Mouse Anti-EGFL7 Recombinant Antibody; Fab Fragment (HPAB-0003-DJB-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0951WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v1); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0952WJ-F(E) | Mouse Anti-EGFL7 Recombinant Antibody (clone 4F11.v17); Fab Fragment | ELISA | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-902 | Afuco™ Anti-EGFL7 ADCC Recombinant Antibody (Parsatuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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