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Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab) (CAT#: TAB-213)

This product is a humanized (from mouse) IgG1 antibody that can recognize human EPCAM.


See more Engineered Antibody products for EPCAM
Specific Inquiry
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  • Purity:
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  • Gene Expression
  • Datasheet
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Subcellular Location
Figure 1 IF staining of human cell line MCF7
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg
Normal Tissue
Figure 2 Thyroid gland
Figure 2 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg
Figure 4 Kidney
Figure 4 Kidney
(Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM

Specifications

  • Immunogen
  • Synthetic peptide corresponding to residues of Human EpCAM.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • Humanized (from mouse) IgG1
  • Specificity
  • Human EPCAM
  • Species Reactivity
  • Human
  • Clone
  • Tucotuzumab
  • Applications
  • WB, Neut, ELISA, IF, IP, FuncS, FC

Product Property

  • Purification
  • Protein A/G Purified
  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Western Blot, Neutralization, Enzyme-linked Immunosorbent Assay, Immunofluorescence, Immunoprecipitation, Functional Assay, Flow Cytometry.

Target

  • Alternative Names
  • ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial cell adhesion molecule; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1

Related Resources

  • Biosimilar Overview
Please refer to Tucotuzumab Celmoleukin Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tucotuzumab Celmoleukin.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Tucotuzumab"

See other products for "EPCAM"

Mouse Antibody

CAT Product Name Application Type
TAB-701 Anti-Human EpCAM/17-1A Recombinant Antibody (Edrecolomab) ELISA, IP, FC, FuncS, IF, Neut IgG2a - kappa
TAB-0531CL Anti-Human EPCAM Recombinant Antibody (HE2) ELISA, Inhib
TAB-363MZ-S(P) Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-363MZ-S(P)) Confocal, ELISA Mouse scFv
TAB-364MZ-S(P) Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-364MZ-S(P)) NIR (Near-infrared) fluorescence imaging, ELISA Mouse scFv
TAB-365MZ-S(P) Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (TAB-365MZ-S(P)) NIR (Near-infrared) fluorescence imaging, ELISA Mouse scFv

Human Antibody

CAT Product Name Application Type
TAB-106 Anti-Human EPCAM Recombinant Antibody (Adecatumumab) FC, IHC, FuncS, Inhib, Cyt IgG1
TAB-356MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (3-171) FC, ELISA Human antibody
TAB-357MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (7-F17) FC, ELISA Human antibody
TAB-358MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (12-C15) FC, ELISA Human antibody
TAB-359MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (16-G5) FC, ELISA Human antibody

Immunotoxin

CAT Product Name Application Type
AGTO-L013E anti-EPCAM immunotoxin MOC31 (IgG)-PE Cytotoxicity assay, Functional assay
AGTO-L013D anti-EPCAM immunotoxin MOC31 (IgG)-DT Cytotoxicity assay, Functional assay
AGTO-L013G anti-EPCAM immunotoxin MOC31 (IgG)-Gel Cytotoxicity assay, Functional assay
AGTO-L013R anti-EPCAM immunotoxin MOC31 (IgG)-RTA Cytotoxicity assay, Functional assay
AGTO-L013O anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin Cytotoxicity assay, Functional assay

Humanized Antibody

CAT Product Name Application Type
TAB-235CL Human Anti-Human EPCAM Recombinant Antibody (3622W94) Cyt, FC Antibody
TAB-374MZ Anti-Human EPCAM Recombinant Antibody (h12H8B) FC, ELISA Humanized antibody
TAB-375MZ Anti-Human EPCAM Recombinant Antibody (h12H8C) FuncS, Inhib Humanized antibody
TAB-376MZ Anti-Human EPCAM Recombinant Antibody (h2D11B) Cyt, Inhib Humanized antibody
TAB-362MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) Confocal, ELISA Humanized antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1163 Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) IHC-P, WB, ICC, ICC, IF Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-106 Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-213 Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS ADCC enhanced antibody
AFC-TAB-701 Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced ELISA, IP, FC, FuncS, IF, Neut ADCC enhanced antibody

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-2216LY-F(E) Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) ELISA Human Fab
HPAB-2217LY-F(E) Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) ELISA Human Fab
HPAB-2218LY-F(E) Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) ELISA Human Fab
HPAB-2219LY-F(E) Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) ELISA Human Fab
HPAB-2220LY-F(E) Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) ELISA Human Fab

Recombinant Antibody

CAT Product Name Application Type
HPAB-2216LY Human Anti-EPCAM Recombinant Antibody (HPAB-2216LY) ELISA Human IgG
HPAB-2217LY Human Anti-EPCAM Recombinant Antibody (HPAB-2217LY) ELISA Human IgG
HPAB-2218LY Human Anti-EPCAM Recombinant Antibody (HPAB-2218LY) ELISA Human IgG
HPAB-2219LY Human Anti-EPCAM Recombinant Antibody (HPAB-2219LY) ELISA Human IgG
HPAB-2220LY Human Anti-EPCAM Recombinant Antibody (HPAB-2220LY) ELISA Human IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-CN0031 APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer FCM
MHC-CN0032 PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer FCM

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0428-FY-S(P) Mouse Anti-EPCAM Recombinant Antibody; scFv Fragment (HPAB-0428-FY-S(P)) ELISA Mouse scFv
HPAB-0639-YJ-S(P) Mouse Anti-EPCAM Recombinant Antibody (clone ch FU-MK-1); scFv Fragment ELISA, FC, WB Mouse scFv
HPAB-S0026-YC-S(P) Human Anti-EPCAM Recombinant Antibody (clone H79); scFv Fragment ELISA, FC, Cyt Human scFv
HPAB-2050-FY-S(P) Human Anti-EpCAM Recombinant Antibody (clone K53); scFv Fragment FC Human scFv
HPAB-2051-FY-S(P) Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment FC Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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