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IGF1R
Human Anti-IGF1R Recombinant Antibody (TAB-199)

Human Anti-IGF1R Recombinant Antibody (TAB-199) (CAT#: TAB-199)

This product is a recombinant Human antibody that recognizes IGF1R. The antibody was purified by affinity chromatography.

See more Engineered Antibody products for IGF1R

Tested Data
Gene Expression
Datasheet
MSDS
COA

ELISA

Figure 1 Anti-Human IGF1R Antibody (TAB-199) in ELISA

Figure 1 Anti-Human IGF1R Antibody (TAB-199) in ELISA

ELISA analysis of TAB-199 was performed by coating with human IGF1R protein.

The secondary antibody: HRP-Anti-Human IgG (H+L)

Figure 2 Anti-Human IGF1R Antibody (TAB-199) in WB

Figure 2 Anti-Human IGF1R Antibody (TAB-199) in WB

Western blot analysis of TAB-199 was performed with human IGF1R protein.

TAB-199 incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing antigen (0.1μg)
Lane 2: Reducing antigen (0.3μg)
Lane 3: Reducing antigen (0.6μg)

Normal Tissue

Figure 1 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_B_7_5.jpg

Figure 2 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_3.jpg

Figure 3 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_8_4.jpg

Figure 4 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_5.jpg

Figure 5 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_6_6.jpg

Figure 6 Heart muscle
(Cardiomyocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_B_5_6.jpg

Figure 7 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_8.jpg

RNA Expression

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140443-IGF1R

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
Human IgG1, κ

Species Reactivity
Human

Applications
FC, IP, ELISA, Neut, FuncS, IF, ICC, Inhib, WB, Activ, IHC, Block

Related Disease
Cancers

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
The IGF1 antibody has been reported in applications of FC, IP, ELISA, Neut, FuncS, IF, ICC, Inhib, WB, Activ, IHC, Block.

Target

Alternative Names
IGFR; CD221; IGFIR; JTK13

Gene ID
3480

UniProt ID
P08069

Related Resources

Related Signaling Pathways
Related Diseases

Insulin Signaling Pathway

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IGF1R"

Single-domain Antibody

CAT	Product Name	Application	Type
NABL-091	Recombinant Anti-human IGF1R VHH Single Domain Antibody	WB, ELISA, IHC, FC, FuncS	Llama VHH
TAB-096ZJ	Anti-Human IGF-1R Therapeutic Single Domain Antibody (IGF1 R-3)	ELISA, IHC, IF, WB	Single domain antibody
HPAB-1545-FY	Recombinant Llama Anti-IGF1R Single Domain Antibody (m632)	WB, ELISA	Llama VHH
HPAB-1546-FY	Recombinant Llama Anti-IGF1R Single Domain Antibody (m636)	WB, ELISA	Llama VHH
HPAB-1547-FY	Recombinant Llama Anti-IGF1R Single Domain Antibody (m546)	WB, ELISA	Llama VHH

Human Antibody

CAT	Product Name	Application	Type
TAB-078	Anti-Human IGF1 Receptor Recombinant Antibody (Cixutumumab)	IF, IP, Neut, FuncS, ELISA, FC, WB	IgG1 - lambda
TAB-055ZJ-F(E)	Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-055ZJ-F(E))	ELISA	Human Fab
TAB-056ZJ-F(E)	Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-056ZJ-F(E))	ELISA	Human Fab
TAB-057ZJ-F(E)	Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-057ZJ-F(E))	ELISA	Human Fab
TAB-058ZJ-F(E)	Anti-Human IGF-1R Recombinant Antibody Fab Fragment (1A)	ELISA	Human antibody

Immunotoxin

CAT	Product Name	Application	Type
AGTO-L024E	IGF1-PE immunotoxin	Cytotoxicity assay, Functional assay
AGTO-L024D	IGF1-DT immunotoxin	Cytotoxicity assay, Functional assay

Humanized Antibody

CAT	Product Name	Application	Type
TAB-386CL	Humanized Anti-IGF1R Recombinant Antibody (TAB-386CL)	FuncS	Humanized IgG
TAB-035ZJ	Human Anti-IGF1R Recombinant Antibody (TAB-035ZJ)	ELISA, FC	Humanized IgG
TAB-036ZJ	Anti-Human IGF-1R Recombinant Antibody (H0L0 IgGIm(AA))	ELISA, Neut, FC, IHC	Humanized antibody
TAB-037ZJ	Anti-Human IGF-1R Recombinant Antibody (H1L0 IgGIm(AA))	ELISA, Neut, FC, IHC	Humanized antibody
TAB-038ZJ	Human Anti-IGF1R Recombinant Antibody (TAB-038ZJ)	FuncS, IP, Inhib, IF	Humanized IgG1

Fab Fragment Antibody

CAT	Product Name	Application	Type
PFBL-591	Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-14); Fab Fragment	WB, ELISA, FuncS	Mouse Fab
PFBL-592	Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-7); Fab Fragment	WB, ELISA, FuncS	Mouse Fab
HPAB-0210CQ-F(E)	Human Anti-IGF1R Recombinant Antibody (clone 15H12); Fab Fragment	ELISA, FC, Neut	Human Fab
HPAB-0211CQ-F(E)	Human Anti-IGF1R Recombinant Antibody (clone 1H3); Fab Fragment	ELISA, FC, Neut	Human Fab
HPAB-0212CQ-F(E)	Human Anti-IGF1R Recombinant Antibody (clone 11A4); Fab Fragment	ELISA, FC, Block	Human Fab

Mouse Antibody

CAT	Product Name	Application	Type
TAB-009ZJ	Mouse Anti-IGF1R Recombinant Antibody (TAB-009ZJ)	ELISA, FC	Mouse IgG1, κ
TAB-010ZJ	Anti-Human IGF-1R Recombinant Antibody (6E11)	ELISA, Neut, FC, IHC
TAB-011ZJ	Mouse Anti-IGF1R Recombinant Antibody (TAB-011ZJ)	ELISA, FC, WB, Inhib	Mouse IgG2, κ
TAB-012ZJ	Mouse Anti-IGF1R Recombinant Antibody (TAB-012ZJ)	ELISA, FC, WB, Inhib	Mouse IgG2, κ
TAB-013ZJ	Anti-Human IGF-1R Recombinant Antibody (1H7)	WB, Inhib

Chimeric Antibody

CAT	Product Name	Application	Type
TAB-084ZJ	Human Anti-IGF1R Recombinant Antibody (TAB-084ZJ)	WB, Inhib, ELISA, FC	Chimeric (mouse/human) IgG
TAB-085ZJ	Anti-Human IGF-1R Recombinant Antibody (6E11c)	ELISA, FC, IHC, Inhib	Chimeric antibody (mouse/human)
TAB-086ZJ	Human Anti-IGF1R Recombinant Antibody (TAB-086ZJ)	ELISA, FC, Inhib, IP	Chimeric (mouse/human) IgG1
TAB-087ZJ	Anti-Human IGF-1R Recombinant Antibody (ch7C2)	ELISA	Chimeric antibody (mouse/human)
TAB-093ZJ	Anti-Human IGF-1R Recombinant Antibody (ch9E11)	ELISA	Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT	Product Name	Application	Type
BRD-0103MZ	Chicken Anti-CD221 Polyclonal IgY	WB	Chicken antibody

Neutralizing Antibody

CAT	Product Name	Application	Type
NEUT-1075CQ	Mouse Anti-IGF1R Recombinant Antibody (clone alphaIR3)	FC, IP, Neut, ICC, IF	Mouse IgG1
NEUT-1076CQ	Mouse Anti-IGF1R Recombinant Antibody (clone 33255.111)	ELISA, Neut, WB	Mouse IgG1
NEUT-1081CQ	Mouse Anti-IGF1R Recombinant Antibody (clone CBL453)	WB, ELISA, Neut	Mouse IgG1
NEUT-1082CQ	Mouse Anti-IGF1R Recombinant Antibody (clone CBL080)	Neut, WB	Mouse IgG1

Blocking Antibody

CAT	Product Name	Application	Type
NEUT-1077CQ	Mouse Anti-IGF1R Recombinant Antibody (clone 1H7)	FC, Block, IHC, IP, WB	Mouse IgG1, κ
NEUT-1078CQ	Mouse Anti-IGF1R Recombinant Antibody (clone 24-60)	Inhib, ICC, IF, IP, WB	Mouse IgG2a, κ
NEUT-1079CQ	Mouse Anti-IGF1R Recombinant Antibody (clone 17-69)	Inhib, IP	Mouse IgG1
NEUT-1080CQ	Mouse Anti-IGF1R Recombinant Antibody (clone 24-57)	Inhib, IP	Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT	Product Name	Application	Type
MOR-1755	Rabbit Anti-IGF1R Recombinant Antibody (clone DS1755AB)	IP, ELISA	Rabbit IgG
MOR-4684	Rabbit Anti-IGF1R Recombinant Antibody (clone TH198DS)	WB, ELISA	Rabbit IgG
MOR-4685	Rabbit Anti-IGF1R Recombinant Antibody (clone TH199DS)	WB	Rabbit IgG

Neuroscience Antibody

CAT	Product Name	Application	Type
NS-041CN	Mouse Anti-IGF1R Recombinant Antibody (NS-041CN)	ELISA, WB, FC	Mouse IgG
NS-041CN-F(E)	Mouse Anti-IGF1R Recombinant Antibody; Fab Fragment (NS-041CN-F(E))	ELISA, WB, FC	Mouse Fab
NS-041CN-S(P)	Mouse Anti-IGF1R Recombinant Antibody; scFv Fragment (NS-041CN-S(P))	ELISA, WB, FC	Mouse scFv

ADCC Enhanced Antibody

CAT	Product Name	Application	Type
AFC-TAB-199	Afuco™ Anti-IGF1R Recombinant Antibody (AFC-TAB-199), ADCC Enhanced	FC, IP, ELISA, Neut, FuncS, IF	Human IgG1, κ
AFC-TAB-209	Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Robatumumab), ADCC Enhanced	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody
AFC-TAB-736	Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Dalotuzumab), ADCC Enhanced	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody
AFC-TAB-078	Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Cixutumumab), ADCC Enhanced	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody
AFC-TAB-232	Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Figitumumab), ADCC Enhanced	IF, IP, Neut, FuncS, ELISA	ADCC enhanced antibody

Recombinant Antibody

CAT	Product Name	Application	Type
HPAB-0284-YJ	Mouse Anti-IGF1R Recombinant Antibody (HPAB-0284-YJ)	ELISA, FC, Inhib, FuncS	Mouse IgG1, κ
HPAB-0285-YJ	Human Anti-IGF1R Recombinant Antibody (HPAB-0285-YJ)	ELISA, FC, Inhib, FuncS	Chimeric (mouse/human) IgG1, κ
HPAB-1204-FY	Mouse Anti-IGF1R Recombinant Antibody (clone 2C6)	WB, FC, Inhib, FuncS	Mouse IgG1, κ
HPAB-1205-FY	Mouse Anti-IGF1R Recombinant Antibody (clone 9H2)	WB	Mouse IgG1, κ
HPAB-1206-FY	Mouse Anti-IGF1R Recombinant Antibody (clone 6E11)	ELISA, Inhib, WB	Mouse IgG

scFv Fragment Antibody

CAT	Product Name	Application	Type
HPAB-0841-FY-F(E)	Mouse Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-0841-FY-F(E))	IHC	Mouse Fab
HPAB-1548-FY-F(E)	Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-1548-FY-F(E))	ELISA	Human Fab
HPAB-0456-YJ-S(P)	Human Anti-IGF1R Recombinant Antibody (clone DB#2); scFv Fragment	ELISA, Inhib, FuncS	Human scFv
HPAB-0457-YJ-S(P)	Human Anti-IGF1R Recombinant Antibody (clone DB#7); scFv Fragment	ELISA, Inhib, FuncS	Human scFv
HPAB-2063-FY-S(P)	Human Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-2063-FY-S(P))	IA	Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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