Products

Elsilimomab (TAB-239)

Recombinant monoclonal antibody to IL-6. Elsilimomab (also known as B-E8) is a mouse monoclonal antibody and an immunosuppressive drug. It (OPR-003) targets (and blocks) Interleukin-6. It has undergone a number of early stage clinical trails, e.g. for lymphoma and myeloma. It was used as a template to develop a high-affinity, antagonist, fully human anti-IL-6 mAb 1339.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG1
Specificity
Tested positive against native human antigen.
Species Reactivity
Human
Applications
Suitable for use in WB, FuncS, IF, Neut, ELISA, FC, IP and most other immunological methods.
Generic Name
Elsilimomab
Related Disease
Cancers
Target
Alternative Names
Elsilimomab; B-E8; B-E8; IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2
Entrez Gene ID
3569
UniProt ID
P05231

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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