Anti-Human ITGA2 Recombinant Antibody (Vatelizumab) (CAT#: TAB-251)
Recombinant monoclonal antibody to ITGA2. Vatelizumab is an immunomodulator. It binds to integrin alpha 2
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1358_H10_6_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1358_H10_6_selected.jpg
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1591_A6_2_red_green.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1591_A6_2_red_green.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_7_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_7_5.jpg
Figure 4 Colon
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_3.jpg
Figure 5 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_7_4.jpg
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_7_4.jpg
Figure 6 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_5.jpg
Figure 7 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_6_6.jpg
Figure 8 Endometrium
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_6_3.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_6_3.jpg
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
Specifications
- Immunogen
- Whole human keratinocytes.
- Host Species
- undefined
- Derivation
- Humanized
- Type
- IgG4 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in WB, IF, IP, Neut, FuncS, ELISA, FC and most other immunological methods.
- CAS
- 1238217-55-4
- Generic Name
- Vatelizumab
- Related Disease
- Multiple sclerosis (MS)
Product Property
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- Vatelizumab;1238217-55-4;SAR339658;GBR500;ITGA2;integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor);CD49B;integrin alpha-2;CD49b;integrin alpha 2;collagen receptor;VLA-2 subunit alpha;platelet antigen Br;platelet glycoprotein Ia;platelet glycopro
- Gene ID
- 3673
- UniProt ID
- P17301
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Vatelizumab"
Afuco™ Anti-ITGA2 ADCC Recombinant Antibody (Vatelizumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ITGA2. Vatelizumab is an immunomodulator. It binds to integrin alpha 2
See other products for "ITGA2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1212z | Mouse Anti-ITGA2 Recombinant Antibody (clone 26D8) | FC, IHC, FuncS | Mouse IgG1 |
| HPAB-0312-CN | Mouse Anti-ITGA2 Recombinant Antibody (HPAB-0312-CN) | ELISA, IHC, Block | Mouse IgG1, κ |
| HPAB-0313-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0313-CN) | ELISA | Chimeric (mouse/human) IgG1, κ |
| HPAB-0314-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0314-CN) | ELISA | Humanized IgG4, κ |
| MOB-072CQ | Rat Anti-Mouse ITGA2 Antibody | FC | Rat IgG2b |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-714LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-714LC-S(P)) | ELISA | Mouse scFv |
| TAB-715LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-715LC-S(P)) | ELISA | Mouse scFv |
| TAB-716LC-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (TAB-716LC-S(P)) | ELISA | Mouse scFv |
| TAB-714LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-714LC-F(E)) | ELISA | Mouse Fab |
| TAB-715LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-715LC-F(E)) | ELISA | Mouse Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0293MZ | Chicken Anti-ITGA2 Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1542CQ | Recombinant Mouse Anti-ITGA2 Antibody (HAS-4) | FC, IHC-Fr, ICC, IP, BL | IgG2a, κ |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1543CQ | Recombinant Mouse Anti-ITGA2 Antibody (P1E6-C5) | FC, BL, IP, ELISA | IgG1, κ |
| NEUT-1544CQ | Recombinant Armenian Hamster Anti-Itga2 Antibody (HMα2) | FC, IF, IP, BL | IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1871 | Hi-Affi™ Recombinant Rabbit Anti-ITGA2 Monoclonal Antibody (DS1871AB) | ICC, WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0312-CN-S(P)) | ELISA, IHC, Block | Mouse scFv |
| HPAB-0313-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0313-CN-S(P)) | ELISA | Human scFv |
| HPAB-0314-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0314-CN-S(P)) | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0312-CN-F(E)) | ELISA, IHC, Block | Mouse Fab |
| HPAB-0313-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0313-CN-F(E)) | ELISA | Human Fab |
| HPAB-0314-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0314-CN-F(E)) | ELISA | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-251 | Afuco™ Anti-ITGA2 ADCC Recombinant Antibody (Vatelizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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