Products

ibritumomab tiuxetan (TAB-H39)

Recombinant Mouse antibody to Human MS4A1. Ibritumomab tiuxetan, sold under the trade name Zevalin, is a monoclonal antibody radioimmunotherapy treatment for relapsed or refractory, low grade or transformed B cell non-Hodgkin's lymphoma, a lymphoproliferative disorder. The drug uses the monoclonal mouse IgG1 antibody ibritumomab (pronounced as ) in conjunction with the chelator tiuxetan, to which a radioactive isotope (either yttrium-90 or indium-111) is added. Tiuxetan is a modified version of DTPA whose carbon backbone contains an isothiocyanatobenzyl and a methyl group.      

Specifications
Host
Mouse
Derivation
Mouse
Type
IgG1 - kappa
Specificity
MS4A1(membrane-spanning 4-domains subfamily A member 1, CD20) [Homo sapiens]
Species Reactivity
Human
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
Trade name
zevalin
CAS NO.
206181-63-7
Generic Name
ibritumomab tiuxetan
ATC Code
V10XX02 (90Y)
DrugBank
DB00078
UNII
4Q52C550XK
ChEMBL
CHEMBL1201606
Related Disease
Non-Hodgkin's lymphoma (NHL)
Target
Alternative Names
ibritumomab tiuxetan; zevalin; 206181-63-7; DB00078 MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1
Entrez Gene ID
931
UniProt ID
P11836

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved