Recombinant Humanized (from mouse) antibody to Human MS4A1. Obinutuzumab was approved under the tradename obinutuzumab by the US FDA in 2013, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients
Figure 1 B cell counts in the peripheral blood in the different treatment groups.
Flow cytometry analysis of CD19⁺ B cells in the peripheral blood of vehicle and CD20XCD3 bsAB-treated fully humanized NOG mice, 24 hours and 72 hours after first and second CD20XCD3 bsAB administration.
Figure 2 T Cell Counts in the Peripheral Blood in the Different Treatment Groups.
Flow cytometry analysis of CD3⁺ T cells in the peripheral blood of vehicle and CD20XCD3 bsAB-treated fully humanized NOG mice, 24 hours and 72 hours after first and second CD20XCD3 bsAB administration.
Figure 3 Anti-Tumour Activity of CD20XCD3 bsAB, Obinutuzumab, and Gpt + CD20XCD3 bsAB.
Anti-tumour activity of CD20XCD3 bsAB and obinutuzumab as monotherapy or Gpt ⁺ CD20XCD3 bsAB in fully humanized NOG mice.
Figure 4 Analysis of anti-tumor activity in combination treatments of an anti- CD20/CD3 bispecific antibody with Obinutuzumab in human hematopoietic stem-cell humanized mice (HSC-NSG mice) bearing aggressive lymphoma model (OCI-Lyl8 tumor).
Efficacies of vehicle, anti-CD20/CD3 bispecific antibody, Obinutuzumab and combination of anti-CD20/CD3 bispecific antibody and Obinutuzumab.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Obinutuzumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human MS4A1. Obinutuzumab was approved under the tradename obinutuzumab by the US FDA in 2013, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-913-sdAb | Recombinant Anti-human MS4A1 VHH Single Domain Antibody | IP, FC, ChiP, Neut | Llama VHH |
HPAB-M0704-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD25) | ELISA, FuncS | Camelid VHH |
HPAB-M0705-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD16) | ELISA | Camelid VHH |
HPAB-M0706-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone R3CD7) | ELISA | Camelid VHH |
HPAB-M0707-YC | Camelid Anti-MS4A1 Recombinant Antibody (clone 2HCD78) | ELISA | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-422 | Human Anti-MS4A1 Recombinant Antibody (clone 2F2) | WB, ELISA, FuncS | Human IgG1,κ |
PABL-423 | Mouse Anti-MS4A1 Recombinant Antibody (clone GA101) | FC, Activ, Agonist, IF, WB, Cyt, FuncS | Mouse IgG |
FAMAB-0144-CN | Human Anti-MS4A1 Recombinant Antibody (clone C2B8) | WB, ELISA | Chimeric (mouse/human) IgG1 |
HPAB-0742-CN | Human Anti-MS4A1 Recombinant Antibody (HPAB-0742-CN) | ELISA, FC | Human IgG |
HPAB-0743-CN | Human Anti-MS4A1 Recombinant Antibody (HPAB-0743-CN) | ELISA, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-019 | Human Anti-MS4A1 Recombinant Antibody (clone C2H7); Fab Fragment | WB, IF, FuncS | Chimeric (mouse/human) IgG |
PFBL-419 | Human Anti-MS4A1 Recombinant Antibody (clone 2F2); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-420 | Mouse Anti-MS4A1 Recombinant Antibody (clone GA101); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
HPAB-0018-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-0018-FY-F(E)) | FC | Humanized Fab |
HPAB-0021-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody (clone hu3D9); Fab Fragment | FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1635CL | Anti-Human MS4A1 Recombinant Antibody (BVX20) | Inhib | Humanized antibody |
TAB-1636CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1636CL) | ADCC, CDC | Humanized IgG |
TAB-1637CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1637CL) | ADCC, CDC | Humanized IgG |
TAB-1638CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1638CL) | ADCC, CDC | Humanized IgG |
TAB-1639CL | Human Anti-MS4A1 Recombinant Antibody (TAB-1639CL) | ADCC, CDC, Apop | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1701CL | Mouse Anti-MS4A1 Recombinant Antibody (TAB-1701CL) | FuncS | Mouse IgG |
TAB-1701CL-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1701CL-F(E)) | FuncS | Mouse Fab |
PABX-026-S (P) | Recombinant Mouse Anti-CD20 Antibody scFv Fragment (C2H7) | WB, ELISA, FuncS | scFv |
PABX-028-S (P) | Recombinant Human Anti-CD20 Antibody scFv Fragment (Ofatumumab) | WB, ELISA, IF, FuncS | scFv |
TAB-007ML | Anti-Canine MS4A1 Recombinant Antibody (Blontuvetmab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1665CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1665CL-S(P)) | CDC | Mouse scFv |
TAB-1666CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1666CL-S(P)) | CDC | Mouse scFv |
TAB-1667CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1667CL-S(P)) | CDC | Mouse scFv |
TAB-1668CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1668CL-S(P)) | CDC | Mouse scFv |
TAB-1669CL-S(P) | Mouse Anti-MS4A1 Recombinant Antibody; scFv Fragment (TAB-1669CL-S(P)) | CDC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1674CL-F(E) | Anti-Human MS4A1 Recombinant Antibody Fab Fragment (101) | Cyt, ELISA, FuncS, Inhib | |
TAB-1676CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1676CL-F(E)) | ELISA | Human Fab |
TAB-1703CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1703CL-F(E)) | FC, CDC, IP | Human Fab |
TAB-1704CL-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (TAB-1704CL-F(E)) | IP | Human Fab |
PABX-028-F (E) | Recombinant Human Anti-CD20 Antibody Fab Fragment (Ofatumumab) | WB, ELISA, IF, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-059LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
Gly-060LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Gly-063LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (mouse/human) |
Gly-067LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA, FC | Chimeric antibody (mouse/human) |
Gly-097LC | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-134LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-135LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-136LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-137LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
Gly-138LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-142LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/Hyper-galactosylated) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-155LC-1 | Recombinant Anti-Human MS4A1 Antibody (Fc glycosylation/High-mannose glycosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-171LC | Recombinant Anti-Human MS4A1 Antibody (Non-glycosylated) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC066 | PE-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC067 | APC-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC068 | BV421-A*02:01/Human CD20 (SLFLGILSV) MHC Tetramer | FCM | |
MHC-LC4347 | PE-B*07:02/Human MS4A1 (RPKSNIVLL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1751CQ | Mouse Anti-MS4A1 Recombinant Antibody (clone CBLS-211) | Neut, FuncS | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2295 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone DS2295AB) | IHC-Fr, IHC-P | Rabbit IgG |
MOR-4024 | Hi-Affi™ Rabbit Anti-MS4A1 Recombinant Antibody (clone SI88DS) | FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-772 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocrelizumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-016 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Rituximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-028 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ofatumumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-207 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ublituximab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
AFC-TAB-771 | Afuco™ Anti-MS4A1 ADCC Recombinant Antibody (Ocaratuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0528-YJ-S(P) | Mouse Anti-MS4A1 Recombinant Antibody (clone 2F4); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-0529-YJ-S(P) | Mouse Anti-MS4A1 Recombinant Antibody (clone ch2F4); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1883-FY-F(E) | Mouse Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1883-FY-F(E)) | ELISA | Mouse Fab |
HPAB-1885-FY-F(E) | Human Anti-MS4A1 Recombinant Antibody; Fab Fragment (HPAB-1885-FY-F(E)) | ELISA, FC | Human Fab |
HPAB-1954-FY-S(P) | Human Anti-MS4A1 Recombinant Antibody (clone BD31-7); scFv Fragment | Cyt | Humanized scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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