Products

Stamulumab (TAB-888)

Recombinant monoclonal antibody expressed in CHO binding to human Myostatin. Stamulumab is an experimental myostatin inhibiting drug for the treatment of muscular dystrophy (MD). Myostatin is a protein that inhibits the growth of muscle tissue, stamulumab is a recombinant human antibody designed to bind to and inhibit the activity of myostatin. Stamulumab is a G1 immunoglobulin antibody which binds to myostatin and prevents it from binding to its target site, thus inhibiting the growth-limiting action of myostatin on muscle tissue.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG1
Species Reactivity
Human
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
CAS NO.
705287-60-1
Generic Name
Stamulumab
UNII
V43X8G4797
M.W.
137.5 kDa
Related Disease
Muscular dystrophy
Target
Alternative Names
Stamulumab; 705287-60-1; MYO-029; MYO-029; MSTN; myostatin; GDF8, growth differentiation factor 8; growth/differentiation factor 8
Entrez Gene ID
2660
UniProt ID
O14793

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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