Products

capromab pendetide (TAB-018)

Recombinant monoclonal antibody to Human PMSA. Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. Capromab is a mouse monoclonal antibody which recognizes prostate specific membrane antigen (PSMA) from prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single photon emission computed tomography (SPECT).      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG1 - kappa
Specificity
Tested positive against native human antigen
Species Reactivity
Human
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, WB and most other immunological methods.
Trade name
prostascint
CAS NO.
145464-28-4
Generic Name
capromab pendetide
ATC Code
V09IB04
ChEMBL
CHEMBL1201579
Target
Alternative Names
capromab pendetide; prostascint; 145464-28-4; 7E11-C5; CYT-356; CYT-500; Prostascint; Indium (111In) capromab pendetide
Entrez Gene ID
2346
UniProt ID
Q04609

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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