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Recombinant Mouse anti-Human RARG Monoclonal antibody (I6730) (CAT#: MOB-1811CT)

Recombinant Mouse monoclonal antibody to Human RARG, expressed in Chinese Hamster Ovary cells(CHO).


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Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line PC-3
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/if_selected.jpg
Figure 2 IHC staining of human cerebellum
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong nuclear positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/ihc_selected.jpg
Figure 3 IF staining of human cell line MCF7
Figure 3 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/868_B7_2_red_green.jpg
Figure 4 IF staining of human cell line U-2 OS
Figure 4 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/832_A12_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
Glial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_B_8_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_A_8_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_A_8_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_A_9_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Peritubular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Preleptotene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Spermatogonia cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_A_6_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53883/121805_A_7_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (CAPAN-2, MCF7)
Figure 11 RNA cell line category: Cell line enhanced (CAPAN-2, MCF7)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000172819-RARG

Specifications

  • Immunogen
  • Baculovirus-expressed recombinant fragment: ATNKERLFAA GALGPGSGYP GAGFPFAFPG ALRGSPPFEM LSPSFRGLGQ PDLPKEMASL SVETQSTSSE EMVPSSPSPP PPPRVYK, corresponding to N terminal amino acids 2/88 of Human Retinoic Acid Receptor gamma
  • Host Species
  • Mouse
  • Specificity
  • This antibody specifically recognizes RAR gamma but does not recognize RAR alpha and beta.
  • Species Reactivity
  • Human
  • Clone
  • I6730
  • Applications
  • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunoprecipitation; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Format
  • Liquid
  • Concentration
  • 1.0 mg/ml
  • Buffer
  • Preservative: 0.1% Sodium Azide Constituents: PBS
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Target

  • Alternative Names
  • RARG; retinoic acid receptor, gamma; RARC; NR1B3; retinoic acid receptor gamma; RAR-gamma; nuclear receptor subfamily 1 group B member 3; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2;
  • Function
  • DNA binding; metal ion binding; protein binding; receptor activity; retinoic acid receptor activity; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "RARG"

Fab Fragment Antibody

CAT Product Name Application Type
DrMAB-490 Recombinant Human Anti-Human RARG Antibody Fab Fragment, clone D559 IP, IF, ELISA Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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