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Anti-Human RON Recombinant Antibody (Narnatumab) (CAT#: TAB-184)

Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.


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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/44_E6_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_6_6.jpg
Figure 7 Skin
Figure 7 Skin
(Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_1.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164078-MST1R

Specifications

  • Immunogen
  • RE7 cells and MDCK cells overexpressing the human RON receptor in complete Freund`s adjuvant
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1 - kappa
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 1188275-92-4
  • Generic Name
  • Narnatumab
  • MW
  • 145.9 kDa
  • Related Disease
  • Solid tumors

Product Property

  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Narnatumab;1188275-92-4;IMC-RON8;MST1R;macrophage stimulating 1 receptor (c-met-related tyrosine kinase);PTK8, PTK8 protein tyrosine kinase 8 , RON;macrophage-stimulating protein receptor;CD136;CDw136;p185-Ron;MSP receptor;RON variant E2E3;MST1R variant R

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Narnatumab"

Afuco™ Anti-MST1R ADCC Recombinant Antibody (Narnatumab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.

See other products for "MST1R"

Human Antibody

CAT Product Name Application Type
TAB-332CT Anti-Human RON Recombinant Antibody (e01h6) WB, ELISA, FC Human antibody
TAB-332CT-S(P) Anti-Human RON Recombinant Antibody scFv Fragment (e01h6) WB, ELISA, FC Human antibody
TAB-333CT-S(P) Human Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-333CT-S(P)) WB, ELISA, FC, IP Human scFv
TAB-332CT-F(E) Anti-Human RON Recombinant Antibody Fab Fragment (e01h6) WB, ELISA, FC Human antibody
TAB-333CT-F(E) Human Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-333CT-F(E)) WB, ELISA, FC, IP Human Fab

Mouse Antibody

CAT Product Name Application Type
TAB-331CT-S(P) Anti-Human RON Recombinant Antibody scFv Fragment (11H09) WB, ELISA, FC
TAB-334CT-S(P) Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-334CT-S(P)) WB, ELISA, FC, IP Mouse scFv
TAB-335CT-S(P) Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-335CT-S(P)) WB, ELISA, FC, IP Mouse scFv
TAB-331CT-F(E) Anti-Human RON Recombinant Antibody Fab Fragment (11H09) WB, ELISA, FC
TAB-334CT-F(E) Mouse Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-334CT-F(E)) WB, ELISA, FC, IP Mouse Fab

Blocking Antibody

CAT Product Name Application Type
NEUT-1756CQ Recombinant Mouse Anti-MST1R Antibody (CBL312) BL IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1757CQ Recombinant Mouse Anti-MST1R Antibody (MM0478-10F24) Neut IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2309 Hi-Affi™ Recombinant Rabbit Anti-MST1R Monoclonal Antibody (DS2309AB) FC, ICC/IF, IHC-P, IP, WB IgG

Recombinant Antibody

CAT Product Name Application Type
HPAB-0062-CN Human Anti-MST1R Recombinant Antibody (clone MOR07923) IP, ELISA, FC Human IgG
HPAB-0063-CN Human Anti-MST1R Recombinant Antibody (clone MOR07924) IP, ELISA, FC Human IgG
HPAB-0064-CN Human Anti-MST1R Recombinant Antibody (clone MOR07925) IP, ELISA, FC Human IgG
HPAB-0821-CN Human Anti-MST1R Recombinant Antibody (clone MOR07692) WB, ELISA, FC Human IgG1, κ
HPAB-0823-CN Human Anti-MST1R Recombinant Antibody (clone MOR07919) WB, ELISA, FC Human IgG1, κ

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0135-FY-S(P) Human Anti-MST1R Recombinant Antibody (clone sh29B06-78); scFv Fragment WB Humanized scFv
HPAB-0821-CN-S(P) Human Anti-MST1R Recombinant Antibody (clone MOR07692); scFv Fragment WB, ELISA, FC Human scFv
HPAB-0823-CN-S(P) Human Anti-MST1R Recombinant Antibody (clone MOR07919); scFv Fragment WB, ELISA, FC Human scFv
HPAB-J0189-YC-S(P) Mouse Anti-MST1R Recombinant Antibody (clone 17F06); scFv Fragment ELISA, Neut, FuncS Mouse scFv
HPAB-J0190-YC-S(P) Human Anti-MST1R Recombinant Antibody (clone Ch07F01 C102S); scFv Fragment ELISA, Neut, FuncS Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0821-CN-F(E) Human Anti-MST1R Recombinant Antibody (clone MOR07692); Fab Fragment WB, ELISA, FC Human Fab
HPAB-0823-CN-F(E) Human Anti-MST1R Recombinant Antibody (clone MOR07919); Fab Fragment WB, ELISA, FC Human Fab
HPAB-687-FY-F(E) Mouse Anti-MST1R Recombinant Antibody (clone 07F01); Fab Fragment Inhib, ELISA, FC Mouse Fab
HPAB-688-FY-F(E) Mouse Anti-MST1R Recombinant Antibody (clone 29B06); Fab Fragment Inhib, ELISA, FC Mouse Fab
HPAB-689-FY-F(E) Mouse Anti-MST1R Recombinant Antibody (clone 18H09); Fab Fragment Inhib, ELISA, FC Mouse Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-184 Afuco™ Anti-MST1R ADCC Recombinant Antibody (Narnatumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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