Anti-Human Tenascin C/TNC Recombinant Antibody (Tenatumomab) (CAT#: TAB-877)

Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.


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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
IHC

Figure 1 Tenascin-C expression was evaluated with tenatumomab antibody.

Figure 1 Tenascin-C expression was evaluated with tenatumomab antibody.

Cases were graded according to scoring intensity as strong.

Gritti, G., Gianatti, A., Petronzelli, F., De Santis, R., Pavoni, C., Rossi, R. L., ... & Barbui, A. M. (2018). Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy. Oncotarget, 9(11), 9766.

IHC

Figure 2 Tenascin-C expression in the different T-cell NHL subtypes.

Figure 2 Tenascin-C expression in the different T-cell NHL subtypes.

ALCL: anaplastic large cell lymphoma; ALK: anaplastic large cell lymphoma kinase.

Gritti, G., Gianatti, A., Petronzelli, F., De Santis, R., Pavoni, C., Rossi, R. L., ... & Barbui, A. M. (2018). Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy. Oncotarget, 9(11), 9766.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG2b
  • Species Reactivity
  • Human
  • Applications
  • IHC
  • Generic Name
  • Tenatumomab
  • UNII
  • 7C201CLB71
  • Related Disease
  • Cancers

Product Property

  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Applications

  • Application Notes
  • The Human Tenascin C/TNC antibody has been reported in applications of Immunohistochemistry.

Target

  • Alternative Names
  • Tenatumomab;ST2146;TNC;tenascin C;hexabrachion (tenascin C, cytotactin) , HXB;tenascin;hexabrachion (tenascin);MGC167029;TN;GP 150-225;cytotactin;neuronectin;myotendinous antigen;tenascin-C isoform 14/AD1/16;glioma-associated-extracellular matrix antigen;

Related Resources

  • Biosimilar Overview
Please refer to Tenatumomab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tenatumomab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Tenatumomab"

Afuco™ Anti-TNC ADCC Recombinant Antibody (Tenatumomab), ADCC Enhanced
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.

See other products for "Tnc"

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0810MZ Chicken Anti-Tenascin C Polyclonal IgY WB Chicken antibody
BRD-0910MZ Chicken Anti-Tenascin C Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2050CQ Rat Anti-TNC Recombinant Antibody (clone CBL402) WB, ICC, Neut Rat IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3601 Rabbit Anti-TNC Recombinant Antibody (clone DS3601AB) WB, IHC, ICC Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-877 Afuco™ Anti-TNC ADCC Recombinant Antibody (Tenatumomab), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF ADCC enhanced antibody

Single-domain Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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