Recombinant Human Antibody (5J8) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 Therapeutic efficacy of MAb 5J8 against disease caused bythe 1918 influenza A(H1N1) virus in mice.
Mice were inoculated onday 0 and treated on day 1 with the indicated antibody and dose. In each group, six mice were monitored every other day for survival.
Krause, J. C., Tsibane, T., Tumpey, T. M., Huffman, C. J., Basler, C. F., & Crowe, J. E. (2011). A broadly neutralizing human monoclonal antibody that recognizes a conserved, novel epitope on the globular head of the influenza H1N1 virus hemagglutinin. Journal of virology, 85(20), 10905-10908.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-203 | Recombinant Human Anti-IAV HA Antibody (3.1) | WB, ELISA, FuncS | IgG |
PABL-204 | Recombinant Human Anti-IAV HA Antibody (39.29) | Neut, FuncS | IgG |
PABL-205 | Recombinant Human Anti-IAV HA Antibody (1957) | WB, Neut, FuncS | IgG |
PABL-206 | Recombinant Human Anti-IAV HA Antibody (1F1) | WB, ELISA, FuncS | IgG |
PABL-208 | Recombinant Human Anti-IAV HA Antibody (65C6) | WB, ELISA, Neut, FuncS | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-203 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (3.1) | WB, ELISA, FuncS | Fab |
PFBL-204 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (39.29) | Neut, FuncS | Fab |
PFBL-205 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (1957) | WB, Neut, FuncS | Fab |
PFBL-206 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (1F1) | WB, ELISA, FuncS | Fab |
PFBL-207 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (5J8) | WB, ELISA, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-184 | Recombinant Human Anti-H1N1 HA Antibody Fab Fragment (UCA) | WB, ELISA | Fab |
PFBZ-186 | Recombinant Human Anti-H2N2 HA Antibody Fab Fragment (2G1) | Neut | Fab |
FAMAB-0254-YC-S(P) | Recombinant Mouse Anti-HA Antibody scFv Fragment (H153-70A12) | ELISA | Mouse scFv |
FAMAB-0277-YC-S(P) | Recombinant Mouse Anti-HA Antibody scFv Fragment (T1-107) | ELISA | Mouse scFv |
HPAB-S0058-YC-S(P) | Mouse Anti-HA Recombinant Antibody (clone HC19); scFv Fragment | Neut | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-262CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D3-4) | WB, FC, IP | Human antibody |
MRO-263CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-2) | WB, FC, IP | Human antibody |
MRO-264CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-3) | WB, FC, IP | Human antibody |
MRO-265CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-4) | WB, FC, IP | Human antibody |
MRO-266CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-5) | WB, FC, IP | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-068 | Recombinant Mouse Anti-Hemagglutinin (HA) Antibody (1F1) | FuncS | IgG |
PABX-069 | Recombinant Mouse Anti-Hemagglutinin (HA) Antibody (S139/1) | Neut, FuncS | IgG |
PABX-070 | Recombinant Mouse Anti-HA1 Antibody (Fab17/9) | WB, ELISA, Neut, FuncS | IgG |
PABX-068-F (E) | Recombinant Mouse Anti-Hemagglutinin(HA) Antibody Fab Fragment (1F1) | WB, ELISA, FuncS | Fab |
PABX-069-F (E) | Recombinant Mouse Anti-Hemagglutinin(HA) Antibody Fab Fragment (S139/1 ) | ELISA, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-070-S (P) | Recombinant Mouse Anti-HA1 Antibody scFv Fragment (Fab17/9) | WB, ELISA, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4209 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI287DS) | ELISA, ICC/IF, IF, FC | IgG |
MOR-4210 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI288DS) | ELISA, ICC/IF, IF, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1169-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1169-FY) | Neut | Llama VHH |
HPAB-1170-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1170-FY) | Neut | Llama VHH |
HPAB-1171-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1171-FY) | Neut | Llama VHH |
HPAB-1172-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1172-FY) | Neut | Llama VHH |
HPAB-1173-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1173-FY) | Neut | Llama VHH |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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