Recombinant Human Antibody (AVFluIgG03) is capable of binding to IAV HA, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IAV HA mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IAV HA proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This human monoclonal antibody bound to the globular head of hemagglutinin (HA) with distinct epitope specificities, neutralization potencies and breadth.
Figure 1 Inhibition of mAb AVFluIgG03 against HA-mediated virus-receptor binding.
Binding of the A/Vietnam/1203/ 04 H5N1 pseudovirus to MDCK cells was expressed as a percentage of the reading obtained in the absence of antibody, which was set at 100%.
Wu, R., Li, X., Leung, H. C., Cao, Z., Qiu, Z., Zhou, Y., ... & He, Y. (2014). A novel neutralizing antibody against diverse clades of H5N1 influenza virus and its mutants capable of airborne transmission. Antiviral research, 106, 13-23.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NABG-078 | Recombinant Anti-IAV HA VHH Single Domain Antibody | FC, CA, IP, FuncS | Llama VHH |
HPAB-0344CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (SD38) | ELISA, Neut | Llama VHH |
HPAB-0345CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (SD36) | ELISA, Neut | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H33 | Anti-IAV HA Recombinant Antibody (Firivumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
TAB-027ML | Anti-IAV HA Recombinant Antibody (Gedivumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
TAB-438CQ | Anti-IAV HA Recombinant Antibody (Navivumab) | ELISA, IHC, FC, IP, IF, BL | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-077 | Recombinant Mouse Anti-IAV HA Antibody scFv Fragment (BH151) | Neut | scFv |
PSBW-077 | Recombinant Mouse Anti-IAV HA Antibody scFv Fragment (HC19) | Neut | scFv |
PSBL-483 | Human Anti-IAV HA Recombinant Antibody; scFv Fragment (PSBL-483) | Neut | Human scFv |
HPAB-0406-WJ-S(P) | Human Anti-IAV HA Recombinant Antibody; scFv Fragment (HPAB-0406-WJ-S(P)) | ELISA | Human scFv |
HPAB-0407-WJ-S(P) | Human Anti-IAV HA Recombinant Antibody; scFv Fragment (HPAB-0407-WJ-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0652CQ | Recombinant Mouse Anti-IAV HA Antibody (pSAN13.4.1) | ELISA | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-343 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (6639) | ELISA, Neut | Human Fab |
PFBC-344 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (56.a.09) | ELISA, FC, Neut | Human Fab |
PFBC-345 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (31.b.09) | ELISA, FC, Neut | Human Fab |
PFBC-346 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (16.a.26) | ELISA, FC, Neut | Human Fab |
PFBC-347 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (16.g.07) | ELISA, FC, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-027ML | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Gedivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-438CQ | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Navivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-H33 | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Firivumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YC213 | H-2Kd/Influenza A virus Haemagglutinin (IYSTVASSL) MHC Pentamer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0204WJ | Mouse Anti-IAV HA Recombinant Antibody (clone H5.16) | ELISA, WB, Neut | Mouse IgG |
FAMAB-0205WJ | Mouse Anti-IAV HA Recombinant Antibody (clone H5.22) | ELISA, WB, Neut | Mouse IgG |
FAMAB-0206WJ | Mouse Anti-IAV HA Recombinant Antibody (clone H5.24) | ELISA, WB, Neut | Mouse IgG |
FAMAB-0207WJ | Mouse Anti-IAV HA Recombinant Antibody (clone H5.31) | ELISA, WB, Neut | Mouse IgG |
FAMAB-0208WJ | Mouse Anti-IAV HA Recombinant Antibody (clone H5.36) | ELISA, WB, Neut | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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