Anti-IFNAR Recombinant Antibody (Anifrolumab) (CAT#: TAB-722)
Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.
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SDS-PAGE
Figure 1 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in SDS-PAGE
SDS-PAGE analysis of TAB-722 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of TAB-722 was greater than 95% as determined by SDS-PAGE.
SEC-HPLC
Figure 2 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in HPLC
The purity of TAB-722 was greater than 95% as determined by SEC-HPLC.
ELISA
Figure 3 Anti-IFNAR Recombinant Antibody (Anifrolumab) (TAB-722) in ELISA
ELISA analysis of TAB-722 was performed by coating with human IFNAR1 protein (His Tag).
The secondary antibody: HRP-anti-human IgG
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, IHC and most other immunological methods.
- CAS
- 1326232-46-5
- Generic Name
- anifrolumab
- MW
- 145.12 kDa
- Related Disease
- Diffuse scleroderma
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- anifrolumab;1326232-46-5;MEDI-546;interferon-α/β receptor;IFNAR
Related Resources
Please refer to Anifrolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Anifrolumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Anifrolumab"
Afuco™ Anti-IFNAR ADCC Recombinant Antibody (Anifrolumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.
See other products for "IFNAR"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1570-VHH | Recombinant Anti-Human IFNAR VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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