Anti-Human IGF-1R Recombinant Antibody (9E11) (CAT#: TAB-015ZJ)
Recombinant monoclonal antibody to insulin-like growth factor 1 receptor. 9E11 is a mouse monoclonal antibody that can be potentially used in the treatment of breast cancer.
Specific Inquiry
FC
Figure 1 Flow cytometric analysis with monoclonal antibodies (MAbs) 9E11.
7C2 and 9E11 specifically stained P6 cells expressing the IGF-1R but did not cross-react with the insulin receptor (IR).
Keyhanfar, M., Forbes, B. E., Cosgrove, L. J., Wallace, J. C., & Booker, G. W. (2006). Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor. Hybridoma, 25(4), 230-237.
IP
Figure 2 Immunoprecipitation of type 1 insulin-like growth factor receptor (IGF-1R).
The IGF-1R subunit (95 kDa) and the pro-IGF-1R (200 kDa) were immunoprecipitated from P6 cell lysates using monoclonal antibodies (MAbs) 7C2, 9E11, and the anti-IGF-1R MAb 24-60.
Keyhanfar, M., Forbes, B. E., Cosgrove, L. J., Wallace, J. C., & Booker, G. W. (2006). Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor. Hybridoma, 25(4), 230-237.
IHC
Figure 3 Detection of the type 1 insulin-like growth factor receptor (IGF-1R), IR-A, and IR-B expressed on frozen cells.
Detection of the type 1 insulin-like growth factor receptor (IGF-1R), IR-A, and IR-B expressed on frozen cells.
Keyhanfar, M., Forbes, B. E., Cosgrove, L. J., Wallace, J. C., & Booker, G. W. (2006). Production and characterization of monoclonal antibodies against insulin-like growth factor type 1 receptor. Hybridoma, 25(4), 230-237.
Specifications
- Immunogen
- Recombinant soluble IGF-IR
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 9E11
- Applications
- FC, IP, IHC, ELISA
- Related Disease
- Breast cancer
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- IGF1R; insulin-like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
- Gene ID
- 3480
- UniProt ID
- P08069
Related Resources
Insulin Signaling Pathway
Endocrine Resistance
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1121z | Mouse Anti-IGF1R Recombinant Antibody (clone 19H8) | WB, ELISA, IHC | Mouse IgG2b |
| PABL-596 | Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-14) | WB, ELISA, FuncS | Mouse IgG |
| PABL-597 | Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-7) | WB, ELISA, FuncS | Mouse IgG |
| MOB-2249MZ | Recombinant Mouse Anti-Human IGF1R Antibody (clone 3D9) | WB | Mouse antibody |
| HPAB-0210CQ | Human Anti-IGF1R Recombinant Antibody (clone 15H12) | ELISA, FC, Neut | Human IgG3, κ |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-091 | Recombinant Anti-human IGF1R VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-096ZJ | Anti-Human IGF-1R Therapeutic Single Domain Antibody (IGF1 R-3) | ELISA, IHC, IF, WB | Single domain antibody |
| HPAB-1545-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m632) | WB, ELISA | Llama VHH |
| HPAB-1546-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m636) | WB, ELISA | Llama VHH |
| HPAB-1547-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m546) | WB, ELISA | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-078 | Anti-Human IGF1 Receptor Recombinant Antibody (Cixutumumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - lambda |
| TAB-056ZJ-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (TAB-056ZJ-S(P)) | ELISA | Human scFv |
| TAB-057ZJ-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (TAB-057ZJ-S(P)) | ELISA | Human scFv |
| TAB-058ZJ-S(P) | Anti-Human IGF-1R Recombinant Antibody scFv Fragment (1A) | ELISA | Human antibody |
| TAB-052ZJ-F(E) | Anti-Human IGF-1R Recombinant Antibody Fab Fragment (18) | ELISA, FC, IF, IP | Human antibody |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L024E | IGF1-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L024D | IGF1-DT immunotoxin | Cytotoxicity assay, Functional assay |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-371CL | Afuco™ Anti-Human IGF1R Antibody, ADCC Enhanced (AFC-371CL) | ELISA | ADCC enhanced antibody |
| AFC-TAB-199 | Afuco™ Anti-IGF1R Recombinant Antibody (AFC-TAB-199), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, κ |
| AFC-TAB-209 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Robatumumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-736 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Dalotuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-078 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Cixutumumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-591 | Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-14); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBL-592 | Mouse Anti-IGF1R Recombinant Antibody (clone mAb 83-7); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| HPAB-0069-YJ-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-0069-YJ-S(P)) | ELISA, Block, FC, FuncS | Human scFv |
| HPAB-1945-FY-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-1945-FY-S(P)) | Inhib | Human scFv |
| HPAB-2063-FY-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-2063-FY-S(P)) | IA | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-009ZJ) | ELISA, FC | Mouse IgG1, κ |
| TAB-010ZJ | Anti-Human IGF-1R Recombinant Antibody (6E11) | ELISA, Neut, FC, IHC | |
| TAB-011ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-011ZJ) | ELISA, FC, WB, Inhib | Mouse IgG2, κ |
| TAB-012ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-012ZJ) | ELISA, FC, WB, Inhib | Mouse IgG2, κ |
| TAB-013ZJ | Anti-Human IGF-1R Recombinant Antibody (1H7) | WB, Inhib |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-035ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-035ZJ) | ELISA, FC | Humanized IgG |
| TAB-036ZJ | Anti-Human IGF-1R Recombinant Antibody (H0L0 IgGIm(AA)) | ELISA, Neut, FC, IHC | Humanized antibody |
| TAB-037ZJ | Anti-Human IGF-1R Recombinant Antibody (H1L0 IgGIm(AA)) | ELISA, Neut, FC, IHC | Humanized antibody |
| TAB-038ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-038ZJ) | FuncS, IP, Inhib, IF | Humanized IgG1 |
| TAB-051ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-051ZJ) | ELISA, IHC, IF, WB | Humanized antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-084ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-084ZJ) | WB, Inhib, ELISA, FC | Chimeric (mouse/human) IgG |
| TAB-085ZJ | Anti-Human IGF-1R Recombinant Antibody (6E11c) | ELISA, FC, IHC, Inhib | Chimeric antibody (mouse/human) |
| TAB-086ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-086ZJ) | ELISA, FC, Inhib, IP | Chimeric (mouse/human) IgG1 |
| TAB-087ZJ | Anti-Human IGF-1R Recombinant Antibody (ch7C2) | ELISA | Chimeric antibody (mouse/human) |
| TAB-093ZJ | Anti-Human IGF-1R Recombinant Antibody (ch9E11) | ELISA | Chimeric antibody (mouse/human) |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0103MZ | Chicken Anti-CD221 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1075CQ | Mouse Anti-IGF1R Recombinant Antibody (clone alphaIR3) | FC, IP, Neut, ICC, IF | Mouse IgG1 |
| NEUT-1076CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 33255.111) | ELISA, Neut, WB | Mouse IgG1 |
| NEUT-1081CQ | Mouse Anti-IGF1R Recombinant Antibody (clone CBL453) | WB, ELISA, Neut | Mouse IgG1 |
| NEUT-1082CQ | Mouse Anti-IGF1R Recombinant Antibody (clone CBL080) | Neut, WB | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1077CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 1H7) | FC, Block, IHC, IP, WB | Mouse IgG1, κ |
| NEUT-1078CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 24-60) | Inhib, ICC, IF, IP, WB | Mouse IgG2a, κ |
| NEUT-1079CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 17-69) | Inhib, IP | Mouse IgG1 |
| NEUT-1080CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 24-57) | Inhib, IP | Mouse IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1755 | Rabbit Anti-IGF1R Recombinant Antibody (clone DS1755AB) | IP, ELISA | Rabbit IgG |
| MOR-4684 | Rabbit Anti-IGF1R Recombinant Antibody (clone TH198DS) | WB, ELISA | Rabbit IgG |
| MOR-4685 | Rabbit Anti-IGF1R Recombinant Antibody (clone TH199DS) | WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0084-YC-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-0084-YC-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0085-YC-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-0085-YC-F(E)) | Block, FuncS, FC, ELISA | Human Fab |
| HPAB-0712-FY-S(P) | Mouse Anti-IGF1R Recombinant Antibody (clone AB011); Fab Fragment | FC | Mouse Fab |
| HPAB-0839-FY-S(P) | Mouse Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-0839-FY-S(P)) | IHC | Mouse scFv |
| HPAB-0840-FY-S(P) | Mouse Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-0840-FY-S(P)) | IHC | Mouse scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-041CN | Mouse Anti-IGF1R Recombinant Antibody (NS-041CN) | ELISA, WB, FC | Mouse IgG |
| NS-041CN-F(E) | Mouse Anti-IGF1R Recombinant Antibody; Fab Fragment (NS-041CN-F(E)) | ELISA, WB, FC | Mouse Fab |
| NS-041CN-S(P) | Mouse Anti-IGF1R Recombinant Antibody; scFv Fragment (NS-041CN-S(P)) | ELISA, WB, FC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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