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Anti-IGF-1R Therapeutic Antibody scFv Fragment (7C10) (TAB-014ZJ-S(P))

Recombinant monoclonal antibody binds specifically to the human insulin-like growth factor I receptor IGF-IR and specifically inhibits the tyrosine kinase activity of IGF-IR receptor. 7C10 significantly inhibits the phosphorylation of the β subunit of IGF-IR.      

Specifications
Immunogen
Recombinant IGF-IR
Host
Mouse
Specificity
Human
Species Reactivity
Human
Clone
7C10
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Neutralization; Immunoprecipitation
Related Disease
Breast cancers, Antitumor
Target
Alternative Names
IGF1R; insulin-like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; IGF-I receptor; soluble IGF1R variant 1
Entrez Gene ID
3480
UniProt ID
P08069

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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