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Anti-IL-1β (Interleukin 1 beta) Therapeutic Antibody Fab Fragment (IC8) (TAB-230CT-F(E))

Recombinant monoclonal antibody to interleukin 1 beta. IC8 is an antibody intended for the prophylaxis and treatment of inflammation.      

Specifications
Immunogen
Human IL-1β protein
Host
Mouse
Specificity
Human
Species Reactivity
Human
Clone
IC8
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay
Related Disease
Inflammation
Target
Alternative Names
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Entrez Gene ID
3553
UniProt ID
P01584

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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