Anti-Human IL-12p40 Recombinant Antibody (m6F6) (CAT#: TAB-018ZJ)
Recombinant monoclonal antibody to interleukin 12 p40. m6F6 is a mouse monoclonal antibody that can be potentially used in the treatment of crohn disease and autoimmune.
Specific Inquiry
Inhib
Figure 1 Characterization of the receptor inhibition profile of m6F6 and c6F6.
m6F6 and c6F6 neutralized the binding of IL-12 to immobilized IL-12Rβ2 extracellular domain (A) and of IL-23 to immobilized IL-23R extracellular domain (B).
Clarke, A. W., Poulton, L., Wai, H. Y., Walker, S. A., Victor, S. D., Domagala, T., ... & Doyle, A. G. (2010, September). A novel class of anti-IL-12p40 antibodies: Potent neutralization via inhibition of IL-12–IL-12Rβ2 and IL-23–IL-23R. In MAbs(Vol. 2, No. 5, pp. 539-549). Taylor & Francis.
Specifications
- Immunogen
- Human IL-12
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- m6F6
- Applications
- Inhib, ELISA
- Related Disease
- Crohn disease, Autoimmune
Applications
- Application Notes
- This antibody has been tested for use in Inhibition, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- IL12B; interleukin 12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B; interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; IL12; subunit p40; interleukin 12, p40; interleukin-12 beta chain; NK cell stimulatory factor chain 2; cytotoxic lymphocyte maturation factor 40 kDa subunit; natural killer cell stimulatory factor; 40 kD subunit; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Gene ID
- 3593
- UniProt ID
- P29460
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone m6F6"
See other products for "IL-12p40"
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-019ZJ | Mouse Anti-IL-12p40 Recombinant Antibody (TAB-019ZJ) | ELISA, Neut | Mouse IgG |
| TAB-018ZJ-S(P) | Anti-Human IL-12p40 Recombinant Antibody scFv Fragment (m6F6) | ELISA | |
| TAB-019ZJ-S(P) | Mouse Anti-IL-12p40 Recombinant Antibody; scFv Fragment (TAB-019ZJ-S(P)) | ELISA, Neut | Mouse scFv |
| TAB-018ZJ-F(E) | Anti-Human IL-12p40 Recombinant Antibody Fab Fragment (m6F6) | ELISA | |
| TAB-019ZJ-F(E) | Mouse Anti-IL-12p40 Recombinant Antibody; Fab Fragment (TAB-019ZJ-F(E)) | ELISA, Neut | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-041ZJ | Human Anti-IL-12p40 Recombinant Antibody (TAB-041ZJ) | ELISA, Neut | Humanized IgG |
| TAB-041ZJ-S(P) | Human Anti-IL-12p40 Recombinant Antibody; scFv Fragment (TAB-041ZJ-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-041ZJ-F(E) | Human Anti-IL-12p40 Recombinant Antibody; Fab Fragment (TAB-041ZJ-F(E)) | ELISA, Neut | Humanized Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-088ZJ-S(P) | Anti-Human IL-12p40 Recombinant Antibody scFv Fragment (c16E7) | ELISA | Chimeric antibody (mouse/human) |
| TAB-089ZJ-S(P) | Anti-Human IL-12p40 Recombinant Antibody scFv Fragment (c6F6) | ELISA | Chimeric antibody (mouse/human) |
| TAB-088ZJ-F(E) | Anti-Human IL-12p40 Recombinant Antibody Fab Fragment (c16E7) | ELISA | Chimeric antibody (mouse/human) |
| TAB-089ZJ-F(E) | Anti-Human IL-12p40 Recombinant Antibody Fab Fragment (c6F6) | ELISA | Chimeric antibody (mouse/human) |
| TAB-092ZJ-F(E) | Human Anti-IL-12p40 Recombinant Antibody; Fab Fragment (TAB-092ZJ-F(E)) | ELISA, Neut | Chimeric antibody (mouse/human) |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-018ZJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.