Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (TAB-210CT-F(E)) (CAT#: TAB-210CT-F(E))

This product is a recombinant mouse antibody Fab fragment that recognizes IL-18R1 or IL-18Rα (interleukin-18R1 or interleukin-18Rα). The antibody was purified by affinity chromatography.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • DNA plasmid expressing both chains (alpha and beta) of human IL-18 receptor
  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human IL-18R1 or IL-18Rα (interleukin-18R1 or interleukin-18Rα)
  • Species Reactivity
  • Human, Monkey
  • Applications
  • Used for immunoassay techniques such as: Flow Cytometry; Enzyme-linked Immunosorbent Assay; Ibhibition
  • Related Disease
  • Chronic obstructive pulmonary disease (COPD)

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "IL18R1"

Immunotoxin

CAT Product Name Application Type
AGTO-G042E IL-18-PE immunotoxin Cytotoxicity assay, Function study
AGTO-G042D IL-18-DT immunotoxin Cytotoxicity assay, Function study

Humanized Antibody

CAT Product Name Application Type
TAB-211CT Human Anti-IL18R1 Recombinant Antibody (TAB-211CT) FC, ELISA, Ibhibition Humanized antibody
TAB-211CT-S(P) Human Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-211CT-S(P)) FC, ELISA, Ibhibition Humanized scFv
TAB-211CT-F(E) Human Anti-IL18R1 Recombinant Antibody; Fab Fragment (TAB-211CT-F(E)) FC, ELISA, Ibhibition Humanized Fab

Neutralizing Antibody

Rabbit Monoclonal Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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