Recombinant Human Antibody (ACZ885) is capable of binding to IL-1β(IL1F2), expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-IL-1β(IL1F2) mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-IL-1β(IL1F2) proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This is a human IgG1κ monoclonal antibody that neutralizes IL-1β by competing for binding to IL-1RI and therefore blocking signaling by the corresponding antigen:antibody complex.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-161 | Anti-Human IL1 beta Recombinant Antibody (Gevokizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG2 - kappa |
TAB-233CT-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-233CT-S(P)) | ELISA | Humanized scFv |
TAB-236CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (huSK48-E26) | ELISA, Neut | Humanized antibody |
TAB-544LC | Anti-human IL1B Recombinant Antibody, Humanized (TAB-544LC) | ELISA | Humanized antibody |
TAB-549LC | Human Anti-IL1B Recombinant Antibody (TAB-549LC) | ELISA, SPR, Inhib | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-239 | Human Anti-IL1B Recombinant Antibody (clone YC129); scFv Fragment | WB, IHC, FuncS | Human scFv |
HPAB-0916-WJ-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0916-WJ-S(P)) | ELISA | Humanized scFv |
HPAB-0917-WJ-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0917-WJ-S(P)) | WB, ELISA, Block | Humanized scFv |
HPAB-0918-WJ-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0918-WJ-S(P)) | ELISA | Humanized scFv |
HPAB-1266WJ-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-1266WJ-S(P)) | ELISA, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-232CT | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (ch47F11) | Inhibition | Chimeric antibody (mouse/human) |
TAB-237CT | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (chSK48-E26) | ELISA, Neut | Chimeric antibody (mouse/human) |
TAB-232CT-F(E) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (ch47F11) | Inhibition | Chimeric antibody (mouse/human) |
TAB-237CT-F(E) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (chSK48-E26) | ELISA, Neut | Chimeric antibody (mouse/human) |
TAB-543LC-F(E) | Anti-human IL1B Fab Fragment, Chimeric | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-230CT-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-230CT-S(P)) | ELISA | Mouse scFv |
TAB-231CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (47F11) | Inhibition | |
TAB-234CT-S(P) | Rabbit Anti-IL1B Recombinant Antibody; scFv Fragment (TAB-234CT-S(P)) | FC, ELISA, Neut | Rabbit scFv |
TAB-235CT-S(P) | Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody scFv Fragment (SK48-E26) | ELISA, Neut | |
TAB-548LC-F(E) | Rabbit Anti-IL1B Recombinant Antibody; Fab Fragment (TAB-548LC-F(E)) | ELISA, SPR | Rabbit Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-550LC-F(E) | Anti-human IL1B Fab Fragment (9.5.2) | ELISA | Human antibody |
TAB-551LC-F(E) | Anti-human IL1B Fab Fragment (5.5.1) | ELISA | Human antibody |
TAB-552LC-F(E) | Anti-human IL1B Fab Fragment (8.18.1) | ELISA | Human antibody |
TAB-553LC-F(E) | Anti-human IL1B Fab Fragment (6.20.1) | ELISA | Human antibody |
TAB-554LC-F(E) | Anti-human IL1B Fab Fragment (6.33.1) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0282MZ | Chicken Anti-Interleukin-1β Polyclonal IgY | WB, Indirect ELISA | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1271CQ | Recombinant Mouse Anti-IL1B Antibody (CBL665) | Neut | IgG1 |
NEUT-1272CQ | Mouse Anti-IL1B Recombinant Antibody (clone 4M27) | IHC, Neut, WB | Mouse IgG2 |
NEUT-1273CQ | Mouse Anti-IL1B Recombinant Antibody (clone 8516.311) | ELISA, WB, Neut | Mouse IgG1 |
NEUT-1275CQ | Mouse Anti-IL1B Recombinant Antibody (clone 2805R) | ELISA, Neut, WB, ICC | Mouse IgG1 |
NEUT-1276CQ | Mouse Anti-IL1B Recombinant Antibody (clone CBL697) | Neut, ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1274CQ | Mouse Anti-IL1B Recombinant Antibody (clone B-A15) | Block, FC | Mouse IgG1 |
NEUT-1285CQ | Mouse Anti-IL1B Recombinant Antibody (clone H1b-27) | ELISA, ELISPOT, Block | Mouse IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1798 | Rabbit Anti-IL1B Recombinant Antibody (clone DS1798AB) | WB | Rabbit IgG |
MOR-4237 | Rabbit Anti-IL1B Recombinant Antibody (clone SI316DS) | ELISA | Rabbit IgG |
MOR-4238 | Rabbit Anti-IL1B Recombinant Antibody (clone SI317DS) | ELISA | Rabbit IgG |
MOR-4239 | Rabbit Anti-IL1B Recombinant Antibody (clone SI318DS) | ELISA | Rabbit IgG |
MOR-4605 | Rabbit Anti-IL1B Recombinant Antibody (clone TH118DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0030-YC | Human Anti-IL1B Recombinant Antibody (clone B1) | Inhib, WB, ELISA | Humanized IgG1, κ |
HPAB-0031-YC | Human Anti-IL1B Recombinant Antibody (clone ABT2-76) | ELISA, Neut | Human IgG |
HPAB-0032-YC | Human Anti-IL1B Recombinant Antibody (clone AAL160) | Neut, Block | Human IgG1, κ |
HPAB-0330-FY | Mouse Anti-IL1B Recombinant Antibody (clone 048-Ab-1) | In vivo, ELISA | Mouse IgG |
HPAB-0331-FY | Mouse Anti-IL1B Recombinant Antibody (clone 048-Ab-3) | In vivo, ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0241CQ-F(E) | Human Anti-IL1B Recombinant Antibody; Fab Fragment (HPAB-0241CQ-F(E)) | ELISA, FC, Neut | Humanized Fab |
HPAB-0729-FY-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0729-FY-S(P)) | ELISA, Neut | Mouse scFv |
HPAB-0730-FY-S(P) | Mouse Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0730-FY-S(P)) | ELISA, Neut | Mouse scFv |
HPAB-0858-FY-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0858-FY-S(P)) | Neut | Humanized scFv |
HPAB-0859-FY-S(P) | Human Anti-IL1B Recombinant Antibody; scFv Fragment (HPAB-0859-FY-S(P)) | Neut | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-021 | Afuco™ Anti-IL1B ADCC Recombinant Antibody (Canakinumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-161 | Afuco™ Anti-IL1B ADCC Recombinant Antibody (Gevokizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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