Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (ch47F11) (CAT#: TAB-232CT-F(E))

Recombinant monoclonal antibody to interleukin 1 beta. ch47F11 is a chimeric(human/mouse) antibody intended for the prophylaxis and treatment of inflammation.


Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Host Species
  • Human
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • ch47F11
  • Applications
  • Used for immunoassay techniques such as: Inhibition
  • Related Disease
  • Inflammation

Target

  • Alternative Names
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone ch47F11"

See other products for "IL1B"

Recombinant Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-232CT Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (ch47F11) Inhibition Chimeric antibody (mouse/human)
TAB-237CT Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (chSK48-E26) ELISA, Neut Chimeric antibody (mouse/human)
TAB-237CT-F(E) Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (chSK48-E26) ELISA, Neut Chimeric antibody (mouse/human)
TAB-543LC-S(P) Anti-human IL1B scFv Fragment, Chimeric ELISA Chimeric antibody (mouse/human)
TAB-543LC-F(E) Anti-human IL1B Fab Fragment, Chimeric ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0282MZ Chicken Anti-Interleukin-1β Polyclonal IgY WB, Indirect ELISA Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1274CQ Mouse Anti-IL1B Recombinant Antibody (clone B-A15) Block, FC Mouse IgG1
NEUT-1285CQ Mouse Anti-IL1B Recombinant Antibody (clone H1b-27) ELISA, ELISPOT, Block Mouse IgG2b, κ

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-021 Afuco™ Anti-IL1B ADCC Recombinant Antibody (Canakinumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-161 Afuco™ Anti-IL1B ADCC Recombinant Antibody (Gevokizumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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