Anti-human IL1B Recombinant Antibody (9.5.2) (TAB-550LC) (CAT#: TAB-550LC)

Recombinant monoclonal antibody 9.5.2 is a human antibody that specifically binds to human IL-1β and can be potentially used in the treatment of arthritis and osteoporosis.


Specific Inquiry
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  • Published Data
  • Gene Expression
  • Datasheet
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Inhib

Figure 1 The percent inhibition of IL-1p-induced IL-6 production in MRC-5 cells for various antibodies.

Figure 1 The percent inhibition of IL-1p-induced IL-6 production in MRC-5 cells for various antibodies.

Inhib

Figure 2 The percent inhibition of ILl p-induced IL-8 production in human whole blood for various antibodies.

Figure 2 The percent inhibition of ILl p-induced IL-8 production in human whole blood for various antibodies.

Inhib

Figure 3 The percent inhibition of IL-6 production for Ab 9.5.2, Ab 5.5.1, and anakinra (KINERET m) in vivo.

Figure 3 The percent inhibition of IL-6 production for Ab 9.5.2, Ab 5.5.1, and anakinra (KINERET m) in vivo.

Upward triangles represent 9.5.2 IgG4, and downward triangles represent 5.5.1 IgG4.

FuncS

Figure 4 Myeloperoxidase (MPO) activity in the lungs of BALB/C mice treated with either IL-I P alone or in combination with mAb 9.5.2 or an isotype control.

Figure 4 Myeloperoxidase (MPO) activity in the lungs of BALB/C mice treated with either IL-I P alone or in combination with mAb 9.5.2 or an isotype control.


Specifications

  • Immunogen
  • Recombinant human IL-lbeta
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • 9.5.2
  • Applications
  • ELISA, Inhib, FuncS
  • Related Disease
  • Arthritis, osteoporosis

Applications

  • Application Notes
  • This antibody has been tested for use in Inhibition and Functional Assay.

Target

  • Alternative Names
  • IL1B; IL1-BETA; IL1F2; IL-1; Interleukin-1 Beta; Catabolin; Interleukin 1, Beta; Pro-Interleukin-1-Beta

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 9.5.2"

See other products for "IL1B"

Human Antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-232CT Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (ch47F11) Inhibition Chimeric antibody (mouse/human)
TAB-237CT Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (chSK48-E26) ELISA, Neut Chimeric antibody (mouse/human)
TAB-237CT-F(E) Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody Fab Fragment (chSK48-E26) ELISA, Neut Chimeric antibody (mouse/human)
TAB-543LC Anti-human IL1B Recombinant Antibody, Chimeric (TAB-543LC) ELISA Chimeric antibody (mouse/human)
TAB-543LC-F(E) Anti-human IL1B Fab Fragment, Chimeric ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0282MZ Chicken Anti-Interleukin-1β Polyclonal IgY WB, Indirect ELISA Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-1274CQ Mouse Anti-IL1B Recombinant Antibody (clone B-A15) Block, FC Mouse IgG1
NEUT-1285CQ Mouse Anti-IL1B Recombinant Antibody (clone H1b-27) ELISA, ELISPOT, Block Mouse IgG2b, κ

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-021 Afuco™ Anti-IL1B ADCC Recombinant Antibody (Canakinumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-161 Afuco™ Anti-IL1B ADCC Recombinant Antibody (Gevokizumab), ADCC Enhanced ELISA, FC, IP, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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