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Anti-IL1RAP scFv (1F5) (TAB-0380CL-S(P))

The anti-IL1RAP antibody specifically bind to the membrane-bound form of IL1RAP, which is a co-receptor for IL1 that function in the IL1 receptor signal transduction complex and is also expressed on cancer cells and caner stem cells. The specific antibody can be used in the treatment of hematopoietic cell cancers such as acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and chronic myelomoncytic leukemia (CMML).      

Specifications
Immunogen
AC Pep-1 peptide (conjugated to keyhole limpet hemocyanin)
Host
Mouse
Specificity
Human
Clone
1F5
Related Disease
Acute myeloid leukemia (AML), chronic myeloid leukemia (CML), chronic myelomoncytic leukemia (CMML)
Target
Alternative Names
IL1RAP; interleukin 1 receptor accessory protein; IL1R3; C3orf13; IL-1RAcP; interleukin-1 receptor accessory protein; IL-1R3; interleukin-1 receptor 3
Entrez Gene ID
3556
UniProt ID
A8K6K4

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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