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Anti-IL1RL2 Fab (89A12) (TAB-0539CL-F(E))

This antibody can block IL36 ligand-mediated signaling (α, β and/or γ), which can be used for the treatment of epithelial-mediated inflammation/fibrosis in diseases such as psoriasis, inflammatory bowel disease, scleroderma, COPD, and chronic kidney disease.      

Specifications
Immunogen
Recombinantly produced human IL-36R (ECD-extracellular domain: amino acids 20-332 of Genbank Accession #NP_003845) protein
Host
Mouse
Specificity
Human
Clone
89A12
Related Disease
Epithelial-mediated inflammation/fibrosis in diseases such as psoriasis, inflammatory bowel disease, scleroderma, COPD, and chronic kidney disease
Target
Alternative Names
IL1RL2; interleukin 1 receptor-like 2; IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2; interleukin-1 receptor-like 2; IL-36 receptor
Entrez Gene ID
8808
UniProt ID
Q9HB29

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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