Anti-human IL20 Recombinant Antibody (FLB5M5) (TAB-565LC) (CAT#: TAB-565LC)

This antibody is a recombinant IgG specific for interleukin 20 (IL20), derived from human. It is capable of recognizing and binding with human IL-20 and can be potentially used in the research of inflammatory diseases. This product has been determined using Enzyme-linked immunosorbent assay and Inhibition assay.


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Inhib

Figure 1 Inhibition of IL-20-induced proliferation by various antibodies: mAb E7, FLB5, and FLB5M5.

Figure 1 Inhibition of IL-20-induced proliferation by various antibodies: mAb E7, FLB5, and FLB5M5.

FuncS

Figure 2 Results from prevention of arthritis (measured with arthritis score (AS)) by treatments with different doses (1 mg/kg, 3 mg/kg, or 9 mg/kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.

Figure 2 Results from prevention of arthritis (measured with arthritis score (AS)) by treatments with different doses (1 mg/kg, 3 mg/kg, or 9 mg/kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.

FuncS

Figure 3 Results from prevention of arthritis (measured with hind-paw thickness) by treatments with different doses (1 mg/kg, 3 mg/kg, or 9 mg kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.

Figure 3 Results from prevention of arthritis (measured with hind-paw thickness) by treatments with different doses (1 mg/kg, 3 mg/kg, or 9 mg kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.

FuncS

Figure 4 Results from prevention of arthritis (measured with body weight) by treatments with different doses (1 mg/kg, 3 mg kg, or 9 mg/kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.

Figure 4 Results from prevention of arthritis (measured with body weight) by treatments with different doses (1 mg/kg, 3 mg kg, or 9 mg/kg) of hFLB5M5 and compared with treatment using Enbrel (6 mg/kg) as a positive control, in a rat rheumatoid arthritis model.


Specifications

  • Host Species
  • Human
  • Derivation
  • LTM Library
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • FLB5M5
  • Applications
  • ELISA, Inhib, FuncS
  • Related Disease
  • Inflammatory diseases

Applications

  • Application Notes
  • This antibody has been tested for use in Inhibition and Functional Assay.

Target

  • Alternative Names
  • IL20; interleukin 20; IL-20; IL10D; ZCYTO10; interleukin-20; cytokine Zcyto10; four alpha helix cytokine

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Human Antibody

CAT Product Name Application Type
TAB-H34 Anti-Human IL20 Recombinant Antibody (Fletikumab) IF, IP, Neut, FuncS, ELISA, FC, ICC IgG4 - kappa
TAB-561LC Anti-human IL20 Recombinant Antibody (20A10) (TAB-561LC) ELISA, Neut, SPR Human antibody
TAB-562LC Anti-human IL20 Recombinant Antibody (2A11) (TAB-562LC) ELISA, Neut, SPR Human antibody
TAB-563LC Anti-human IL20 Recombinant Antibody (7D1) (TAB-563LC) ELISA, Neut, SPR Human antibody
TAB-564LC Anti-human IL20 Recombinant Antibody (6E11) (TAB-564LC) ELISA, Neut Human antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1324CQ Rat Anti-Il20 Recombinant Antibody (clone CBL626) Neut Rat IgG2b

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4256 Rabbit Anti-IL20 Recombinant Antibody (clone SI336DS) ELISA Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H34 Afuco™ Anti-IL20 ADCC Recombinant Antibody (Fletikumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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