Recombinant monoclonal antibody Risankizumab is a humanized monoclonal antibody that specifically binds to human IL-23A and can be potentially used in the treatment of Crohn's disease, psoriasis, psoriatic arthritis and asthma.
Figure 1 Correlation of change from baseline to Week 12 in CDEIS score with [A] Log2-fold change [FC] from baseline in faecal calprotectin; and [B] Log2FC from baseline in faecal lactoferrin in the colon in the 600-mg risankizumab dose group. [C] Correlation of changes from baseline to Week 12 in faecal calprotectin levels with S-100A8 transcript expression in the colon in the 600-mg risankizumab dose group.
Figure 2 [A] Differentially expressed miRNAs in colon biopsies 12 weeks after treatment with 600 mg risankizumab [Log2FC from baseline] versus baseline. Coloured dots represent each of the differentially expressed miRNAs. Levels of miR-223-3p in [B] colon and [C] faeces in patients receiving placebo and 600 mg risankizumab at baseline and Week 12. Whiskers represent the 10th and 90th percentiles of expression. Datasets for figures [B] and [C] were analysed for statistical significance using two-tailed unpaired Student's t-test; *p < 0.05. [D] Correlation of Log2FC in faecal calprotectin levels with Log2FC in miR-223-3p expression in colon biopsy tissue in the 600-mg risankizumab dose group. The red line represents the regression line of best fit [Pearson's correlation = 0.432] and the blue line represents a regression line of 1. Cpm, counts per million; FC, fold change; ns, not significant; RCC, reporter code count.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
NAB-1953-VHH | Recombinant Anti-human IL23A VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
TAB-005LC-VHH | Anti-human IL23A Recombinant Antibody (119A3) (TAB-005LC-VHH) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-420CL | Anti-Human IL23A Recombinant Antibody (BI 655066) | FuncS | Antibody |
TAB-622LC | Human Anti-IL23A Recombinant Antibody (TAB-622LC) | ELISA | Human antibody |
TAB-613LC-F(E) | Anti-human IL23A Fab Fragment (ST883/885) | ELISA | Human antibody |
TAB-622LC-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (TAB-622LC-F(E)) | ELISA | Human Fab |
TAB-008ML | Anti-Human IL23A Recombinant Antibody (Brazikumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG2, λ |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-241 | Human Anti-IL23A Recombinant Antibody (clone CNTO1959); scFv Fragment | WB, ELISA, FuncS | Human scFv |
HPAB-0860-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0860-FY-F(E)) | Inhib | Mouse Fab |
HPAB-0861-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-0861-FY-F(E)) | Inhib | Mouse Fab |
HPAB-1560-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1560-FY-F(E)) | ELISA | Mouse Fab |
HPAB-1561-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1561-FY-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-606LC | Anti-human IL23A Recombinant Antibody (E11E7) (TAB-606LC) | ELISA, Neut | |
TAB-614LC | Anti-human IL23A Recombinant Antibody (8C9) (TAB-614LC) | ELISA, Inhib | |
TAB-615LC | Anti-human IL23A Recombinant Antibody (2H6) (TAB-615LC) | ELISA, Inhib | |
TAB-621LC | Mouse Anti-IL23A Recombinant Antibody (TAB-621LC) | ELISA, WB, Neut | Mouse IgG |
TAB-606LC-S(P) | Anti-human IL23A scFv Fragment (E11E7) | ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-607LC | Anti-human IL23A Recombinant Antibody (E11E7Chimera) (TAB-607LC) | ELISA, Neut, FuncS | Chimeric antibody (rat/human) |
TAB-607LC-S(P) | Anti-human IL23A scFv Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
TAB-607LC-F(E) | Anti-human IL23A Fab Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-616LC | Anti-human IL23A Recombinant Antibody (A3M0) (TAB-616LC) | ELISA, FC, Inhib, FuncS | Humanized antibody |
TAB-617LC | Anti-human IL23A Recombinant Antibody (A3M1) (TAB-617LC) | ELISA, FC, Inhib | Humanized antibody |
TAB-618LC | Anti-human IL23A Recombinant Antibody (A3N1) (TAB-618LC) | ELISA, FC, Inhib | Humanized antibody |
TAB-605LC-S(P) | Anti-human IL23A scFv Fragment (FM303) | ELISA | Humanized antibody |
TAB-608LC-S(P) | Anti-human IL23A scFv Fragment (21-4) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1335CQ | Mouse Anti-IL23A Recombinant Antibody (clone HNU2319) | FuncS, Neut | Mouse IgG1, κ |
NEUT-1336CQ | Rabbit Anti-IL23A Recombinant Antibody (VMC198) | WB, Neut | Rabbit IgG2b |
NEUT-1337CQ | Human Anti-IL23A Recombinant Antibody (clone CBL1018) | Neut | Human IgG1, κ |
NEUT-1338CQ | Mouse Anti-IL23A Recombinant Antibody (clone M066) | Neut | Mouse IgG1 |
NEUT-1339CQ | Mouse Anti-Il23a Recombinant Antibody (clone CBL1028) | Neut | Mouse IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4335 | Rabbit Anti-IL23A Recombinant Antibody (clone SI424DS) | ELISA | Rabbit IgG |
MOR-4615 | Rabbit Anti-IL23A Recombinant Antibody (clone TH128DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0516-CN | Human Anti-IL23A Recombinant Antibody (HPAB-0516-CN) | ELISA, FC, Neut | Human IgG4, κ |
HPAB-0860-FY | Mouse Anti-IL23A Recombinant Antibody (HPAB-0860-FY) | WB | Mouse IgG |
HPAB-0861-FY | Mouse Anti-IL23A Recombinant Antibody (HPAB-0861-FY) | Inhib | Mouse IgG |
HPAB-0865-FY | Mouse Anti-IL23A Recombinant Antibody (HPAB-0865-FY) | ELISA | Mouse IgG |
HPAB-0866-FY | Mouse Anti-IL23A Recombinant Antibody (HPAB-0866-FY) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-875 | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Tildrakizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-620LC | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Risankizumab), ADCC Enhanced | ELISA | ADCC enhanced antibody |
AFC-TAB-008ML | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Brazikumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0860-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0860-FY-S(P)) | Inhib | Mouse scFv |
HPAB-0861-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0861-FY-S(P)) | Inhib | Mouse scFv |
HPAB-0865-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0865-FY-S(P)) | ELISA | Mouse scFv |
HPAB-0866-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0866-FY-S(P)) | ELISA | Mouse scFv |
HPAB-0867-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0867-FY-S(P)) | ELISA | Mouse scFv |
There are currently no Customer reviews or questions for TAB-620LC-F(E). Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.