Anti-human IL23A Recombinant Antibody (E11E7) (TAB-606LC) (CAT#: TAB-606LC)
Recombinant monoclonal antibody E11E7 is a rat monoclonal antibody that specifically binds to human IL-23. Binding of the antibody to IL-23 as measured by SPR and the Kd value is 0.1 nM. It inhibits the binding of IL-23 to IL-23R. It also can be potentially used in the research of psoriasis, Crohn's disease and multiple sclerosis.
Specific Inquiry
Neut
Figure 1 A graphical representation showing E11E7 or E11E7Chimera-mediated neutralization of IL-23-induced IL-17 secretion by mouse splenocytes.
Values are expressed as percentage inhibition compared to IL-23-induced IL-17 secretion by mouse splenocytes in the absence of antibody.
ELISA
Figure 2 Graphical representations showing detection of recombinant IL-23 using E11E7 as a capture antibody as performed via ELISA (A) and the detection of native IL-23, by E11E7, produced by the cell line THP-1 when stimulated with Pokeweed Mitogen (PWM) and lipopolysaccharide (LPS), as measured by ELISA (B).
Specifications
- Immunogen
- Plasmids allow the secretion of soluble IL-23
- Host Species
- Rat
- Specificity
- Human
- Clone
- E11E7
- Applications
- ELISA, Neut
- Related Disease
- Psoriasis, Crohn's disease and multiple sclerosis
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-Linked Immunosorbent Assay and Neutralization.
Target
- Alternative Names
- IL23A; interleukin 23, alpha subunit p19; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor
- Gene ID
- 51561
- UniProt ID
- Q9NPF7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1953-VHH | Recombinant Anti-human IL23A VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
| TAB-005LC-VHH | Anti-human IL23A Recombinant Antibody (119A3) (TAB-005LC-VHH) | ELISA | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-420CL | Anti-Human IL23A Recombinant Antibody (BI 655066) | FuncS | Antibody |
| TAB-622LC | Human Anti-IL23A Recombinant Antibody (TAB-622LC) | ELISA | Human antibody |
| TAB-613LC-F(E) | Anti-human IL23A Fab Fragment (ST883/885) | ELISA | Human antibody |
| TAB-622LC-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (TAB-622LC-F(E)) | ELISA | Human Fab |
| TAB-008ML | Anti-Human IL23A Recombinant Antibody (Brazikumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG2, λ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-241 | Human Anti-IL23A Recombinant Antibody (clone CNTO1959); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| HPAB-655-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody (clone 8C92H6); scFv Fragment | ELISA | Mouse scFv |
| HPAB-656-FY-S(P) | Human Anti-IL23A Recombinant Antibody (clone A5M20); scFv Fragment | Inhib | Humanized scFv |
| HPAB-AP118-YC-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-AP118-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-AP119-YC-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-AP119-YC-S(P)) | ELISA | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-082 | Human Anti-IL23A Recombinant Antibody (PABW-082) | Neut | Human IgG |
| PABW-154 | Mouse Anti-IL23A Recombinant Antibody (clone CNTO4088) | WB | Mouse IgG |
| MOB-0967CT | Recombinant Mouse anti-Human IL23A Monoclonal antibody (IMU3847) | IHC-P, IP, WB | |
| HPAB-0517-CN | Mouse Anti-IL23A Recombinant Antibody (HPAB-0517-CN) | ELISA, FC | Mouse IgG |
| HPAB-0518-CN | Human Anti-IL23A Recombinant Antibody (HPAB-0518-CN) | ELISA, FC | Humanized IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-607LC | Anti-human IL23A Recombinant Antibody (E11E7Chimera) (TAB-607LC) | ELISA, Neut, FuncS | Chimeric antibody (rat/human) |
| TAB-607LC-S(P) | Anti-human IL23A scFv Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
| TAB-607LC-F(E) | Anti-human IL23A Fab Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-614LC | Anti-human IL23A Recombinant Antibody (8C9) (TAB-614LC) | ELISA, Inhib | |
| TAB-621LC | Mouse Anti-IL23A Recombinant Antibody (TAB-621LC) | ELISA, WB, Neut | Mouse IgG |
| TAB-614LC-F(E) | Anti-human IL23A Fab Fragment (8C9) | ELISA, FC | |
| TAB-615LC-F(E) | Anti-human IL23A Fab Fragment (2H6) | ELISA, FC | |
| TAB-621LC-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (TAB-621LC-F(E)) | ELISA, WB | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-616LC | Anti-human IL23A Recombinant Antibody (A3M0) (TAB-616LC) | ELISA, FC, Inhib, FuncS | Humanized antibody |
| TAB-617LC | Anti-human IL23A Recombinant Antibody (A3M1) (TAB-617LC) | ELISA, FC, Inhib | Humanized antibody |
| TAB-618LC | Anti-human IL23A Recombinant Antibody (A3N1) (TAB-618LC) | ELISA, FC, Inhib | Humanized antibody |
| TAB-605LC-S(P) | Anti-human IL23A scFv Fragment (FM303) | ELISA | Humanized antibody |
| TAB-608LC-S(P) | Anti-human IL23A scFv Fragment (21-4) | ELISA | Humanized antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1335CQ | Mouse Anti-IL23A Recombinant Antibody (clone HNU2319) | FuncS, Neut | Mouse IgG1, κ |
| NEUT-1336CQ | Rabbit Anti-IL23A Recombinant Antibody (VMC198) | WB, Neut | Rabbit IgG2b |
| NEUT-1337CQ | Human Anti-IL23A Recombinant Antibody (clone CBL1018) | Neut | Human IgG1, κ |
| NEUT-1338CQ | Mouse Anti-IL23A Recombinant Antibody (clone M066) | Neut | Mouse IgG1 |
| NEUT-1339CQ | Mouse Anti-Il23a Recombinant Antibody (clone CBL1028) | Neut | Mouse IgG2b, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4335 | Rabbit Anti-IL23A Recombinant Antibody (clone SI424DS) | ELISA | Rabbit IgG |
| MOR-4615 | Rabbit Anti-IL23A Recombinant Antibody (clone TH128DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-875 | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Tildrakizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-620LC | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Risankizumab), ADCC Enhanced | ELISA | ADCC enhanced antibody |
| AFC-TAB-008ML | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Brazikumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0860-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0860-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0861-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0861-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0865-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0865-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0866-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0866-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0867-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0867-FY-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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