Anti-human IL23A Recombinant Antibody (21-4) (TAB-608LC) (CAT#: TAB-608LC)
This recombinant monoclonal antibody is a humanized monoclonal antibody that specifically binds to human IL-23. It has potent affinity against IL23A and the Kd value of this antibody against IL23A measured by SPR is 0.388 nM. This antibody demonstrates specific binding to IL-23 and did not significantly bind to either IL-12p40 or IL-23p 19 as demonstrated by ELISA. It can also be potentially used in the research of psoriasis, Crohn's disease and multiple sclerosis.
Specific Inquiry
ELISA
Figure 1 A series of graphical representations showing binding of humanized forms of E11E7 to IL-23 but not significantly binding to IL-12p40 or IL-23p19.
Blank refers to assay conditions in which the coating antigen is omitted.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- 21-4
- Applications
- ELISA
- Related Disease
- Psoriasis, Crohn's disease and multiple sclerosis
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- IL23A; interleukin 23, alpha subunit p19; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor
- Gene ID
- 51561
- UniProt ID
- Q9NPF7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 21-4"
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1953-VHH | Recombinant Anti-human IL23A VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
| TAB-005LC-VHH | Anti-human IL23A Recombinant Antibody (119A3) (TAB-005LC-VHH) | ELISA | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-420CL | Anti-Human IL23A Recombinant Antibody (BI 655066) | FuncS | Antibody |
| TAB-613LC | Anti-human IL23A Recombinant Antibody (ST883/885) (TAB-613LC) | ELISA | Human antibody |
| TAB-622LC | Human Anti-IL23A Recombinant Antibody (TAB-622LC) | ELISA | Human antibody |
| TAB-613LC-F(E) | Anti-human IL23A Fab Fragment (ST883/885) | ELISA | Human antibody |
| TAB-622LC-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (TAB-622LC-F(E)) | ELISA | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-241 | Human Anti-IL23A Recombinant Antibody (clone CNTO1959); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| HPAB-1234-FY-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1234-FY-F(E)) | ELISA | Human Fab |
| HPAB-1235-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1235-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1236-FY-F(E) | Mouse Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1236-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1237-FY-F(E) | Human Anti-IL23A Recombinant Antibody; Fab Fragment (HPAB-1237-FY-F(E)) | ELISA | Humanized Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABW-154 | Mouse Anti-IL23A Recombinant Antibody (clone CNTO4088) | WB | Mouse IgG |
| MOB-0967CT | Recombinant Mouse anti-Human IL23A Monoclonal antibody (IMU3847) | IHC-P, IP, WB | |
| HPAB-0516-CN | Human Anti-IL23A Recombinant Antibody (HPAB-0516-CN) | ELISA, FC, Neut | Human IgG4, κ |
| HPAB-655-FY | Mouse Anti-IL23A Recombinant Antibody (clone 8C92H6) | ELISA | Mouse IgG |
| HPAB-656-FY | Human Anti-IL23A Recombinant Antibody (clone A5M20) | Inhib | Humanized IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-607LC | Anti-human IL23A Recombinant Antibody (E11E7Chimera) (TAB-607LC) | ELISA, Neut, FuncS | Chimeric antibody (rat/human) |
| TAB-607LC-S(P) | Anti-human IL23A scFv Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
| TAB-607LC-F(E) | Anti-human IL23A Fab Fragment (E11E7Chimera) | ELISA | Chimeric antibody (rat/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-621LC | Mouse Anti-IL23A Recombinant Antibody (TAB-621LC) | ELISA, WB, Neut | Mouse IgG |
| TAB-606LC-S(P) | Anti-human IL23A scFv Fragment (E11E7) | ELISA | |
| TAB-614LC-S(P) | Anti-human IL23A scFv Fragment (8C9) | ELISA, FC | |
| TAB-615LC-S(P) | Anti-human IL23A scFv Fragment (2H6) | ELISA, FC | |
| TAB-621LC-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (TAB-621LC-S(P)) | ELISA, WB | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-605LC-S(P) | Anti-human IL23A scFv Fragment (FM303) | ELISA | Humanized antibody |
| TAB-608LC-S(P) | Anti-human IL23A scFv Fragment (21-4) | ELISA | Humanized antibody |
| TAB-609LC-S(P) | Anti-human IL23A scFv Fragment (8-22) | ELISA | Humanized antibody |
| TAB-610LC-S(P) | Anti-human IL23A scFv Fragment (6-22) | ELISA | Humanized antibody |
| TAB-611LC-S(P) | Anti-human IL23A scFv Fragment (1-4) | ELISA | Humanized antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1335CQ | Mouse Anti-IL23A Recombinant Antibody (clone HNU2319) | FuncS, Neut | Mouse IgG1, κ |
| NEUT-1336CQ | Rabbit Anti-IL23A Recombinant Antibody (VMC198) | WB, Neut | Rabbit IgG2b |
| NEUT-1337CQ | Human Anti-IL23A Recombinant Antibody (clone CBL1018) | Neut | Human IgG1, κ |
| NEUT-1338CQ | Mouse Anti-IL23A Recombinant Antibody (clone M066) | Neut | Mouse IgG1 |
| NEUT-1339CQ | Mouse Anti-Il23a Recombinant Antibody (clone CBL1028) | Neut | Mouse IgG2b, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4335 | Rabbit Anti-IL23A Recombinant Antibody (clone SI424DS) | ELISA | Rabbit IgG |
| MOR-4615 | Rabbit Anti-IL23A Recombinant Antibody (clone TH128DS) | WB | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-875 | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Tildrakizumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-620LC | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Risankizumab), ADCC Enhanced | ELISA | ADCC enhanced antibody |
| AFC-TAB-008ML | Afuco™ Anti-IL23A ADCC Recombinant Antibody (Brazikumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0860-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0860-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0861-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0861-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0865-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0865-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0866-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0866-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-0867-FY-S(P) | Mouse Anti-IL23A Recombinant Antibody; scFv Fragment (HPAB-0867-FY-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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